Use of Pentoxifylline combined with captopril/losartan in hypertensive or diabetic patients: An integrative review of randomized clinical trials

YS Nascimento, YS Nascimento… - Research, Society and …, 2023 - rsdjournal.org
Objective: To perform an integrative literature review to analyze the effects of the use of
Pentoxifylline (PTX) combined and/or compared to captopril or losartan. Methodology: An …

The randomized clinical trial of pentoxifylline for reduction of blood pressure in patients with primary hypertension

H Namdar, S Khiali… - Pharmaceutical …, 2020 - archives.articleproms.com
Background: Pentoxifylline (PTX) is a xanthine derivative with the potential cardiovascular
effects. This study was done to evaluate the impact of pentoxifylline on blood pressure when …

Efficacy and safety of combining pentoxifylline with angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker in diabetic nephropathy: a meta-analysis

ML Tian, Y Shen, ZL Sun, Y Zha - International Urology and Nephrology, 2015 - Springer
Objective Pentoxifylline (PTF) has anti-inflammatory properties, which may be beneficial for
diabetic nephropathy (DN). A meta-analysis was conducted to assess the additive effect of …

Effects of pentoxifylline on inflammatory markers and blood pressure: a systematic review and meta-analysis of randomized controlled trials

D Brie, A Sahebkar, PE Penson, M Dinca… - Journal of …, 2016 - journals.lww.com
Aim: To evaluate the impact of pentoxifylline on blood pressure (BP) and plasma TNF-α, C-
reactive protein (CRP) and IL-6 through a systematic review and meta-analysis of …

Pentoxifylline and arterial hypertension in diabetes mellitus: long-term results in randomized groups

SB Solerte, S Adamo, C Viola… - La Ricerca in Clinica e …, 1985 - europepmc.org
This follow-up study concerns the use of pentoxifylline (PTX) as antihypertensive drug in
randomized diabetic groups. A significant reduction of systolic and diastolic arterial blood …

The effect of pentoxifylline on proteinuria in diabetic kidney disease: a meta-analysis

BB McCormick, A Sydor, A Akbari, D Fergusson… - American Journal of …, 2008 - Elsevier
BACKGROUND: Pentoxifylline is a potential therapeutic agent for diabetic kidney disease
because it has anti-inflammatory, antifibrotic, and hemorheological properties. STUDY …

The effect of a methylxanthine vasodilator: pentoxifylline on the treatment of diabetic nephropathy—a meta-analysis

M Zhang, Y Wang, W Fu, L Sun - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
This meta-analysis aimed to comprehensively evaluate the efficacy and safety of
pentoxifylline (PTF) in the treatment of diabetic nephropathy (DN) and to offer fresh …

Effects of Adding Pentoxifylline to Captopril on Primary Hypertension: A Pilot Randomized Clinical Trial

نامدار, خانی, پوررشید, انتظاری ملکی, طاهر - The Journal of Clinical …‎ - eprints.arums.ac.ir
Because of the key role blood viscosity plays in the regulation of blood pressure (BP) and
the hemorheological effects of pentoxifylline (PTX), this study was conducted to evaluate …

Effects of adding pentoxifylline to captopril on primary hypertension: A pilot randomized clinical trial

H Namdar, E Khani, MH Pourrashid… - The Journal of …, 2020 - Wiley Online Library
Because of the key role blood viscosity plays in the regulation of blood pressure (BP) and
the hemorheological effects of pentoxifylline (PTX), this study was conducted to evaluate …

Pentoxifylline in diabetic kidney disease (VA PTXRx): protocol for a pragmatic randomised controlled trial

DJ Leehey, K Carlson, DJ Reda, I Craig, C Clise… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Diabetic kidney disease (DKD) is the most frequent cause of end-stage renal
disease (ESRD) in the USA and worldwide. Recent experimental and clinical data suggest …