Advances on the roles of m 6A in tumorigenesis

TG Wang, M Ye - Yi Chuan= Hereditas, 2018 - europepmc.org
Predominantly found in mRNA, m 6A methylation of RNA molecules regulates post-
transcriptional gene expression without changing RNA sequence. m 6A methylation alters …

Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword

S Wang, P Chai, R Jia, R Jia - Molecular cancer, 2018 - Springer
Abstract N6-methyladenosine (m 6 A), the most prevalent modification of mammalian RNA,
has received increasing attention. Although m 6 A has been shown to be associated with …

m6A modification: a double-edged sword in tumor development

R Gao, M Ye, B Liu, M Wei, D Ma, K Dong - Frontiers in Oncology, 2021 - frontiersin.org
Modification of m6A, as the most abundant mRNA modification, plays diverse roles in
various biological processes in eukaryotes. Emerging evidence has revealed that m6A …

Exploring the role of m6A modification in cancer

Y Wei, Y Li, C Lu - Proteomics, 2023 - Wiley Online Library
Abstract m6A is one of the most common, abundant, and conserved post‐transcriptional
modifications that regulate broad biological processes in the human body through m6A …

The role of m6A RNA methylation in cancer metabolism

Y An, H Duan - Molecular cancer, 2022 - Springer
Metabolic reprogramming is one of the main characteristics of malignant tumors, which is
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …

Role of m6A RNA methylation in tumorigenesis and development

W LONG, H GUO, J SHENG, R SONG… - Biotechnology …, 2019 - biotech.aiijournal.com
m6A methylation, which was first discovered in 1974, is a kind of methylation modification on
RNA molecule. In recent years, it has become a research hotspot in life science …

New understandings of the genetic regulatory relationship between non-coding RNAs and m6A modification

S Liu, D Xiang - Frontiers in Genetics, 2023 - frontiersin.org
One of the most frequent epigenetic modifications of RNA in eukaryotes is N6
methyladenosine (m6A), which is mostly present in messenger RNAs. Through the influence …

Link between m6A modification and cancers

ZX Liu, LM Li, HL Sun, SM Liu - Frontiers in bioengineering and …, 2018 - frontiersin.org
N6-methyladenosine (m6A) epitranscriptional modification has recently gained much
attention. Through the development of m6A sequencing, the molecular mechanism and …

Multiple functions of m6A RNA methylation in cancer

Y Pan, P Ma, Y Liu, W Li, Y Shu - Journal of hematology & oncology, 2018 - Springer
First identified in 1974, m 6 A RNA methylation, which serves as a predominant internal
modification of RNA in higher eukaryotes, has gained prodigious interest in recent years …

The m6A RNA methylation regulates oncogenic signaling pathways driving cell malignant transformation and carcinogenesis

MB Uddin, Z Wang, C Yang - Molecular cancer, 2021 - Springer
The m 6 A RNA methylation is the most prevalent internal modification in mammalian
mRNAs which plays critical biological roles by regulating vital cellular processes …