[HTML][HTML] Exosome-mediated lnc-ABCA12-3 promotes proliferation and glycolysis but inhibits apoptosis by regulating the toll-like receptor 4/nuclear factor kappa-B …

J Ma, Y Luo, Y Liu, C Chen, A Chen… - The Korean Journal …, 2023 - ncbi.nlm.nih.gov
Esophageal squamous cell carcinoma (ESCC) is a kind of malignant tumor with high
incidence and mortality in the digestive system. The aim of this study is to explore the …

[HTML][HTML] Rectal cancer-derived exosomes activate the nuclear factor kappa B pathway and lung fibroblasts by delivering integrin beta-1

Q Gao, K An, Z Gao, Y Wang, C Ding… - The Korean Journal of …, 2023 - ncbi.nlm.nih.gov
Numerous studies have revealed the importance of tumor-derived exosomes in rectal
cancer (RC). This study aims to explore the influence of tumor-derived exosomal integrin …

Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression

L Wu, X Zhang, B Zhang, H Shi, X Yuan, Y Sun, Z Pan… - Tumor Biology, 2016 - Springer
Exosomes are nano-sized membrane vesicles secreted by both normal and cancer cells.
Emerging evidence indicates that cancer cells derived exosomes contribute to cancer …

CAF-derived exosomes deliver LINC01410 to promote epithelial-mesenchymal transition of esophageal squamous cell carcinoma

Z Shi, T Jiang, B Cao, X Sun, JF Liu - Experimental Cell Research, 2022 - Elsevier
Exosomes mediate cellular communications in cancer by transmitting active molecules.
However, the CAFs-derived molecular determinants that regulate esophageal squamous …

Tumor-associated macrophage-derived exosomes promote the progression of gastric cancer by regulating the P38MAPK signaling pathway and the immune …

Y Wang, K Shang, N Zhang, J Zhao… - Cancer Biotherapy & …, 2021 - liebertpub.com
Objective: To investigate the effects of M2 macrophage-derived exosomes (M2-Exos) on
proliferation, migration, and apoptosis of gastric cancer cells in the tumor microenvironment …

OP16 induces deadly autophagy and apoptosis of cells by inhibiting Akt in esophageal squamous cell carcinoma

G Hou, A Jia, L Yang, Y Zhao, Y Hu, W Zhao… - Molecular and Cellular …, 2020 - Springer
Background OP16, a derivative of the novel ent-kaurene diterpenoid compound separated
from Rabdosia rubescens, has been confirmed for its efficacy and safety in the treatment of …

Exosome-Delivered EGFR Induced by Acidic Bile Salts Regulates Macrophage M2 Polarization to Promote Esophageal Adenocarcinoma Cell Proliferation

C Chen, J Ding, Z Ma, Y Xie, L Zhang… - OncoTargets and …, 2024 - Taylor & Francis
Purpose Chronic gastroesophageal reflux disease (GERD) causes the abnormal reflux of
acid and bile salts, which would induce Barrett's esophagus (BE) and esophageal …

[HTML][HTML] CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer …

T Xiu, Q Guo, F Jing, Y Shi, F Jing - Translational Cancer Research, 2022 - ncbi.nlm.nih.gov
Background Gastric cancer (GC) is one of the most common malignant tumours in China, but
the efficacy of chemotherapy on GC is significantly reduced due to the occurrence of drug …

ML323, a USP1 inhibitor triggers cell cycle arrest, apoptosis and autophagy in esophageal squamous cell carcinoma cells

Y Sun, B Sha, W Huang, M Li, S Zhao, Y Zhang, J Yan… - Apoptosis, 2022 - Springer
Esophageal squamous cell carcinoma (ESCC) is a common digestive cancer with high
mortality rate due to late diagnosis and drug resistance. It is important to identify new …

Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation

JL Qu, XJ Qu, MF Zhao, YE Teng, Y Zhang… - Digestive and liver …, 2009 - Elsevier
BACKGROUND: Exosomes are nanometer-sized vesicles that are released by normal and
neoplastic cells. Previous studies have focused on the interaction between tumour-derived …