Tissue-engineered graft for circumferential esophageal reconstruction in rats

IG Kim, Y Wu, SA Park, H Cho, JW Shin… - JoVE (Journal of …, 2020 - jove.com
The use of biocompatible materials for circumferential esophageal reconstruction is a
technically challenging task in rats and requires an optimal implant technique with nutritional …

Tissue-engineered esophagus via bioreactor cultivation for circumferential esophageal reconstruction

IG Kim, Y Wu, SA Park, H Cho, JJ Choi… - … Engineering Part A, 2019 - liebertpub.com
The use of biomaterials for circumferential esophageal repair is technically challenging in a
rat model, and an optimal scaffold implantation technique with nutritional support is …

[HTML][HTML] Assessment of esophageal reconstruction via bioreactor cultivation of a synthetic scaffold in a canine model

IG Kim, Y Wu, SA Park, JS Choi… - Clinical and …, 2023 - synapse.koreamed.org
Objectives Using tissue-engineered materials for esophageal reconstruction is a technically
challenging task in animals that requires bioreactor training to enhance cellular reactivity …

[HTML][HTML] Long-term regeneration and remodeling of the pig esophagus after circumferential resection using a retrievable synthetic scaffold carrying autologous cells

S La Francesca, JM Aho, MR Barron, EW Blanco… - Scientific reports, 2018 - nature.com
Abstract Treatment of esophageal disease can necessitate resection and reconstruction of
the esophagus. Current reconstruction approaches are limited to utilization of an autologous …

Bioartificial esophagus: where are we now?

EJ Chung - Biomimetic Medical Materials: From Nanotechnology to …, 2018 - Springer
The current treatments for esophageal diseases, such as carcinomas, trauma or congenital
malformations, require surgical intervention and esophageal reconstruction using redundant …

Experimental investigation of esophageal reconstruction with electrospun polyurethane nanofiber and 3D printing polycaprolactone scaffolds using a rat model

H Park, IG Kim, Y Wu, H Cho, JW Shin, SA Park… - Head & …, 2021 - Wiley Online Library
Background We evaluated the outcome of esophageal reconstructions using tissue‐
engineered scaffolds. Method Partial esophageal defects were reconstructed with the …

[HTML][HTML] Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

L Urbani, C Camilli, DE Phylactopoulos… - Nature …, 2018 - nature.com
A tissue engineered oesophagus could overcome limitations associated with oesophageal
substitution. Combining decellularized scaffolds with patient-derived cells shows promise for …

[HTML][HTML] A narrative review of esophageal tissue engineering and replacement: where are we?

L Model, O Wiesel - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Long-gap esophageal defects, whether congenital or acquired, are very difficult to manage.
Any significant surgical peri-esophageal dissection that is performed to allow for potential …

[HTML][HTML] Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats

S Sjöqvist, P Jungebluth, M Ling Lim, JC Haag… - Nature …, 2014 - nature.com
A tissue-engineered oesophageal scaffold could be very useful for the treatment of pediatric
and adult patients with benign or malignant diseases such as carcinomas, trauma or …

Full‐thickness oesophageal regeneration in pig using a polyurethane mucosal cell seeded graft

MR Barron, EW Blanco, JM Aho… - Journal of Tissue …, 2018 - Wiley Online Library
Malignant oesophageal pathology typically requires resection of a portion of oesophagus.
The aim of this study was to investigate attachment and growth of swine oesophageal …