Synergistic combination therapy of lung cancer using paclitaxel-and triptolide-coloaded lipid–polymer hybrid nanoparticles

J Liu, H Cheng, L Han, Z Qiang, X Zhang… - Drug design …, 2018 - Taylor & Francis
Purpose Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer. Lipid–
polymer hybrid nanoparticles (LPNs) combine the advantages of both polymeric …

Combination chemotherapy of lung cancer–co-delivery of docetaxel prodrug and cisplatin using aptamer-decorated lipid–polymer hybrid nanoparticles

R Wu, Z Zhang, B Wang, G Chen, Y Zhang… - Drug design …, 2020 - Taylor & Francis
Purpose Lung cancer is the leading cause of cancer mortality worldwide. Drug resistance is
the major barrier for the treatment of non-small cell lung cancer (NSCLC). The aim of this …

[HTML][HTML] Endothelial growth factor receptor-targeted and reactive oxygen species-responsive lung cancer therapy by docetaxel and resveratrol encapsulated lipid …

Z Song, Y Shi, Q Han, G Dai - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Special targeted therapy like endothelial growth factor receptor (EGFR) targeted therapy is
available for the treatment of advanced non-small cell lung cancer (NSCLC). Biodegradable …

[HTML][HTML] RGD peptide-modified, paclitaxel prodrug-based, dual-drugs loaded, and redox-sensitive lipid-polymer nanoparticles for the enhanced lung cancer therapy

G Wang, Z Wang, C Li, G Duan, K Wang, Q Li… - Biomedicine & …, 2018 - Elsevier
One approach to improve the targeted therapeutic efficiency of lung cancer is to deliver
drugs using nano-scaled systems. In this study, RGD peptide-modified, paclitaxel (PTX) …

Transferrin-decorated protein-lipid hybrid nanoparticle efficiently delivers cisplatin and docetaxel for targeted lung cancer treatment

K Mao, W Zhang, L Yu, Y Yu, H Liu… - Drug Design …, 2021 - Taylor & Francis
Purpose Non-small cell lung cancer (NSCLC) therapy faces the barriers including drug
resistance. A transferrin-functionalized protein-lipid hybrid nanoparticle (PLHN) was …

Lung cancer combination therapy: co-delivery of paclitaxel and doxorubicin by nanostructured lipid carriers for synergistic effect

Y Wang, H Zhang, J Hao, B Li, M Li, W Xiuwen - Drug delivery, 2016 - Taylor & Francis
Context: Paclitaxel (PTX) and doxorubicin (DOX) are widely used for the combined
chemotherapy of solid tumors. However, free drug combination has lower antitumor …

[HTML][HTML] Lipid-coated polymeric nanoparticles for cancer drug delivery

S Krishnamurthy, R Vaiyapuri, L Zhang… - Biomaterials science, 2015 - pubs.rsc.org
Polymeric nanoparticles and liposomes have been the platform of choice for nanoparticle-
based cancer drug delivery applications over the past decade, but extensive research has …

[HTML][HTML] Utilization of polymer-lipid hybrid nanoparticles for targeted anti-cancer therapy

A Mohanty, S Uthaman, IK Park - Molecules, 2020 - mdpi.com
Cancer represents one of the most dangerous diseases, with 1.8 million deaths worldwide.
Despite remarkable advances in conventional therapies, these treatments are not effective …

[HTML][HTML] Lung carcinoma therapy using epidermal growth factor receptor‑targeted lipid polymeric nanoparticles co‑loaded with cisplatin and doxorubicin

Y Nan - Oncology reports, 2019 - spandidos-publications.com
The rate of lung cancer in tuberculosis (TB) patients is 7 to 30% higher than that in healthy
individuals. Conventional chemotherapy of lung cancer shows limited efficiency due to poor …

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

L Zhang, D Zhu, X Dong, H Sun, C Song… - International journal …, 2015 - Taylor & Francis
The purpose of this study was to develop a novel lipid–polymer hybrid drug carrier
comprised of folate (FA) modified lipid-shell and polymer-core nanoparticles (FLPNPs) for …