The 3xTg‐AD mouse develops a progressive Alzheimer′ s disease‐(AD‐) like brain
pathology that causes cognitive‐and neuropsychiatric‐like symptoms of dementia. Since its …

In the present work, we briefly review the evidence on the key role played by the
neuroimmunoendocrine network in the etiopathogenesis of Alzheimer's disease (AD) and …

Physical exercise is considered to exert a positive neurophysiological effect that helps to
maintain normal brain activity in the elderly. Expectations that it could help to fight …

Postmenopausal women may be more vulnerable to cognitive loss and Alzheimer's disease
(AD) than premenopausal women because of their deficiency in estrogens, in addition to …

Abstract Alzheimer's disease (AD), a prevalent form of dementia, is characterized by the
decline of cognitive abilities with age. Available treatment options for AD are limited, making …

Background: Immune system activation is frequently reported in patients with Alzheimer's
disease (AD). However, it remains unknown whether this is a cause, a consequence, or an …

Normal, age-related depletion of the androgen testosterone is a risk factor for Alzheimer's
disease (AD) in men. Previously, we reported that experimental androgen depletion …

In this study, we investigated mice of the TgCRND8 line, an APP transgenic mouse model of
Alzheimer's disease (AD), with respect to behavioral, endocrinological, and …

Physical exercise is suggested for preventing or delaying senescence and Alzheimer's
disease (AD). We have examined its therapeutic value in the advanced stage of AD-like …

Background Hypothalamic dysfunction occurs early in the clinical course of Alzheimer's
disease (AD), likely contributing to disturbances in feeding behavior and metabolic function …