Altered reward sensitivity in female offspring of cocaine-exposed fathers

DK Fischer, RC Rice, AM Rivera, M Donohoe… - Behavioural brain …, 2017 - Elsevier
Recent rodent studies have demonstrated that parental cocaine exposure can influence
offspring behavior, supporting the idea that environmental insults can impact subsequent …

Subtle biobehavioral effects produced by paternal cocaine exposure

CE Killinger, S Robinson, GD Stanwood - Synapse, 2012 - Wiley Online Library
Despite the increased prevalence of cocaine use and abuse in males when compared with
females, possible effects of paternal cocaine exposure on biobehavioral development have …

Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice

AM Yaw, RA Prosser, PC Jones, BJ Garcia… - Behavioural Brain …, 2019 - Elsevier
Paternal cocaine use causes phenotypic alterations in offspring behavior and associated
neural processing. In rodents, changes in first generation (F1) offspring include drug reward …

Impaired cocaine‐induced behavioral plasticity in the male offspring of cocaine‐experienced sires

ME Wimmer, FM Vassoler, SL White… - European Journal of …, 2019 - Wiley Online Library
Our previous work indicated that male, but not female, offspring of cocaine‐experienced
sires display blunted cocaine self‐administration. We extended this line of investigation to …

Paternal cocaine in mice alters social behavior and brain oxytocin receptor density in first generation offspring

AM Yaw, JD Glass, RA Prosser, HK Caldwell - Neuroscience, 2022 - Elsevier
It is well established that the damaging effects of drugs of abuse, such as cocaine, can
extend beyond the user to their offspring. While most preclinical models of the generational …

Enhanced anxiety in the male offspring of sires that self‐administered cocaine

SL White, FM Vassoler, HD Schmidt… - Addiction …, 2016 - Wiley Online Library
We previously showed that paternal cocaine exposure reduced the reinforcing efficacy of
cocaine in male offspring. Here, we sought to determine whether paternal cocaine …

[HTML][HTML] Transcriptomic effects of paternal cocaine-seeking on the reward circuitry of male offspring

N Huang, J Cui, G Fan, T Pan, K Han, K Xu… - Translational …, 2024 - nature.com
It has been previously established that paternal development of a strong incentive
motivation for cocaine can predispose offspring to develop high cocaine-seeking behavior …

Behavioral characterization of adult male and female rhesus monkeys exposed to cocaine throughout gestation

LR Hamilton, PW Czoty, MA Nader - Psychopharmacology, 2011 - Springer
Rationale In utero cocaine exposure has been associated with alterations in the dopamine
(DA) system in monkeys. However, the behavioral outcomes of prenatal cocaine exposure in …

Cocaine treatment and prenatal environment interact to disrupt intergenerational maternal behavior in rats.

JM Johns, DL Elliott, VE Hofler, PW Joyner… - Behavioral …, 2005 - psycnet.apa.org
The link between impaired maternal behavior (MB) and cocaine treatment could result from
drug-induced decreases in maternal reactivity to offspring, prenatal drug exposure (PDE) in …

Increased vulnerability to self-administer cocaine in mice prenatally exposed to cocaine

BA Rocha, AN Mead, BE Kosofsky - Psychopharmacology, 2002 - Springer
Heading Abstract Rationale. At least 40,000 infants born each year in the US are estimated
to have been exposed to crack cocaine and, therefore, may be at risk for increased …