Quantification of PD-L1 expression with 18F-BMS-986192 PET/CT in patients with advanced-stage non–small cell lung cancer

MC Huisman, ALN Niemeijer… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The aim of this work was to quantify the uptake of 18F-BMS-986192, a programmed cell
death ligand 1 (PD-L1) adnectin PET tracer, in patients with non–small cell lung cancer. To …

First-in-humans evaluation of a PD-L1–binding peptide PET radiotracer in non–small cell lung cancer patients

X Zhou, J Jiang, X Yang, T Liu, J Ding… - Journal of Nuclear …, 2022 - Soc Nuclear Med
68Ga-NOTA-WL12 is a peptide-based PET imaging agent. We conducted a first-in-human
study of 68Ga-NOTA-WL12 for PET to study the in vivo biodistribution, metabolism, radiation …

Assessing PD-L1 expression level by radiomic features from PET/CT in nonsmall cell lung cancer patients: an initial result

M Jiang, D Sun, Y Guo, Y Guo, J Xiao, L Wang… - Academic radiology, 2020 - Elsevier
Rationale and Objectives To explore the potential value of radiomic features-derived
approach in assessing PD-L1 expression status in nonsmall cell lung cancer (NSCLC) …

Predicting PD-L1 expression status in patients with non-small cell lung cancer using [18F]FDG PET/CT radiomics

X Zhao, Y Zhao, J Zhang, Z Zhang, L Liu, X Zhao - EJNMMI research, 2023 - Springer
Background In recent years, immune checkpoint inhibitor (ICI) therapy has greatly changed
the treatment prospects of patients with non-small cell lung cancer (NSCLC). Among the …

18F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer

M Jreige, I Letovanec, K Chaba, S Renaud… - European journal of …, 2019 - Springer
Abstract Purpose Anti-PD-1/PD-L1 blockade can restore tumour-specific T-cell immunity and
is an emerging therapy in non-small-cell lung cancer (NSCLC). We investigated the …

Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody

C Christensen, LK Kristensen, MZ Alfsen… - European Journal of …, 2020 - Springer
Purpose Despite remarkable clinical responses and prolonged survival across several
cancers, not all patients benefit from PD-1/PD-L1 immune checkpoint blockade. Accordingly …

Short dynamic FDG-PET imaging protocol for patients with lung cancer

T Torizuka, S Nobezawa, S Momiki… - European journal of …, 2000 - Springer
This positron emission tomography (PET) study was designed to compare 2-[fluorine-18]
fluoro-2-deoxy-D-glucose (FDG) kinetic parameters of tumours derived from imaging frames …

PET imaging of tumor PD-L1 expression with a highly specific nonblocking single-domain antibody

G Lv, X Sun, L Qiu, Y Sun, K Li, Q Liu… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Although immunotherapy through programmed death 1/programmed death ligand 1 (PD-
1/PD-L1) checkpoint blockade has shown impressive clinical outcomes, not all patients …

[HTML][HTML] Prognostic significance of PD-L1 expression and 18F-FDG PET/CT in surgical pulmonary squamous cell carcinoma

M Zhang, D Wang, Q Sun, H Pu, Y Wang, S Zhao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Programmed cell death-ligand 1 (PD-L1) expression is commonly observed in non-small
cell lung cancer (NSCLC). The prognostic value of PD-L1 expression and the maximum …

Molecular imaging of PD-L1 expression and dynamics with the adnectin-based PET tracer 18F-BMS-986192

TS Stutvoet, EL van der Veen, A Kol… - Journal of Nuclear …, 2020 - Soc Nuclear Med
18F-BMS-986192, an adnectin-based human programmed cell death ligand 1 (PD-L1)
tracer, was developed to noninvasively determine whole-body PD-L1 expression by PET …