Alternative splicing in stem cell self-renewal and diferentiation
This chapter provides a review of recent advances in understanding the importance of
alternative pre-messenger RNA splicing in stem cell biology. The majority of transcribed pre …
alternative pre-messenger RNA splicing in stem cell biology. The majority of transcribed pre …
Alternative pre-mRNA splicing in stem cell function and therapeutic potential: A critical review of current evidence
L Cui, Y Zheng, R Xu, Y Lin, J Zheng, P Lin… - International Journal of …, 2024 - Elsevier
Alternative splicing is a crucial regulator in stem cell biology, intricately influencing the
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …
Alternative splicing modulates stem cell differentiation
Stem cells have the surprising potential to develop into many different cell types. Therefore,
major research efforts have focused on transplantation of stem cells and/or derived …
major research efforts have focused on transplantation of stem cells and/or derived …
[HTML][HTML] Alternative splicing: An important mechanism in stem cell biology
Alternative splicing (AS) is an essential mechanism in post-transcriptional regulation and
leads to protein diversity. It has been shown that AS is prevalent in metazoan genomes, and …
leads to protein diversity. It has been shown that AS is prevalent in metazoan genomes, and …
Diversification of stem cell molecular repertoire by alternative splicing
M Pritsker, TT Doniger, LC Kramer… - Proceedings of the …, 2005 - National Acad Sciences
Complete information regarding transcriptional and posttranscriptional gene regulation in
stem cells is necessary to understand the regulation of self-renewal and differentiation …
stem cells is necessary to understand the regulation of self-renewal and differentiation …
Decrypting the genome's alternative messages
B Hartmann, J Valcárcel - Current opinion in cell biology, 2009 - Elsevier
Alternative splicing of messenger RNA (mRNA) precursors affects the majority of human
genes, has a considerable impact on eukaryotic gene function and offers distinct …
genes, has a considerable impact on eukaryotic gene function and offers distinct …
Alternative splicing regulation and cell lineage differentiation
The alternative splicing of precursor mRNA is an essential mechanism for protein diversity. It
plays important biological roles, such as proliferation, differentiation and development of …
plays important biological roles, such as proliferation, differentiation and development of …
Alternative splicing increases complexity of stem cell transcriptome
M Pritsker, IR Lemischka - Cell Cycle, 2006 - Taylor & Francis
Development of highly anticipated stem cell-based therapies requires a
detailedunderstanding of mechanisms regulating biological properties of these cells …
detailedunderstanding of mechanisms regulating biological properties of these cells …
Regulation of alternative pre-mRNA splicing
L Woodley, J Valcárcel - Briefings in Functional Genomics, 2002 - academic.oup.com
The first wave of bioinformatic studies that followed genome and complementary DNA
sequencing projects revealed that alternative splicing of messenger RNA precursors (pre …
sequencing projects revealed that alternative splicing of messenger RNA precursors (pre …
Pre-mRNA splicing: where and when in the nucleus
Alternative splicing is a process to differentially link exon regions in a single precursor
mRNA to produce two or more different mature mRNAs, a strategy frequently used by higher …
mRNA to produce two or more different mature mRNAs, a strategy frequently used by higher …