Safety of belimumab in adult patients with systemic lupus erythematosus: Results of a large integrated analysis of controlled clinical trial data

DJ Wallace, T Atsumi, M Daniels, A Hammer… - Lupus, 2022 - journals.sagepub.com
Objectives Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that
affects multiple organ systems. Belimumab, a targeted human monoclonal antibody, binds to …

Safety and efficacy of belimumab to treat systemic lupus erythematosus in academic clinical practices

JS Hui-Yuen, A Reddy, J Taylor, X Li… - The Journal of …, 2015 - jrheum.org
Objective. To evaluate the use and efficacy of belimumab in academic practices. Belimumab
is a human monoclonal antibody that inhibits soluble B lymphocyte stimulator and has been …

Safety profile of belimumab: pooled data from placebo-controlled phase 2 and 3 studies in patients with systemic lupus erythematosus

DJ Wallace, S Navarra, MA Petri, A Gallacher… - Lupus, 2013 - journals.sagepub.com
Safety data were pooled and analyzed from one phase 2 and two phase 3 double-blind,
placebo-controlled, repeat-dose systemic lupus erythematosus (SLE) trials of belimumab 1 …

Belimumab: review of use in systemic lupus erythematosus

EG Boyce, BE Fusco - Clinical therapeutics, 2012 - Elsevier
BACKGROUND: Belimumab, a monoclonal antibody that inhibits B-lymphocyte stimulating
protein, was the first biologic agent approved for, and the first drug approved in 55 years for …

Update on belimumab for the management of systemic lupus erythematosus

PMK Lutalo, DP D'Cruz - Expert Opinion on Biological Therapy, 2014 - Taylor & Francis
Introduction: Belimumab is a fully humanised mAb against B lymphocyte stimulator (B-LyS).
It is the first biological drug to be licensed and approved by the US FDA and the European …

[HTML][HTML] Usefulness of belimumab in adult patients with systemic lupus erythematosus evaluated using single indexes: a meta-analysis and systematic review

C Yoshijima, Y Suzuki, A Oda, R Tanaka, H Ono… - Current Therapeutic …, 2024 - Elsevier
Background Belimumab is the first antibody drug approved for systemic lupus
erythematosus (SLE), and is a fully human monoclonal antibody that inhibits soluble B …

[HTML][HTML] Real-world effectiveness of belimumab in systemic lupus erythematosus: a systematic literature review

SP Huang, SJ Snedecor, S Nanji, E Lloyd… - Rheumatology and …, 2022 - Springer
Introduction Belimumab is a recombinant human monoclonal antibody that binds to soluble
B-lymphocyte stimulator and inhibits its biological activity. Since receiving approvals for the …

Belimumab in systemic lupus erythematosus: a profile of its use

YN Lamb - Drugs & Therapy Perspectives, 2021 - Springer
Belimumab (Benlysta®), a human immunoglobulin (Ig) G1λ monoclonal antibody targeting B
lymphocyte stimulator, is effective as an add-on to standard therapy in patients with active …

[HTML][HTML] Real-world effectiveness of belimumab in the treatment of systemic lupus erythematosus: pooled analysis of multi-country data from the OBSErve studies

CE Collins, J Cortes-Hernández, MA Garcia… - Rheumatology and …, 2020 - Springer
Introduction The real-world effectiveness of belimumab for systemic lupus erythematosus
(SLE) in six countries was evaluated in the OBSErve program. The aim of this post hoc …

Belimumab for the management of systemic lupus erythematosus

PMK Lutalo, DP D'Cruz - Expert opinion on biological therapy, 2012 - Taylor & Francis
Introduction: In 2011, Belimumab, a fully humanized monoclonal antibody against B
lymphocyte stimulator, became the first biological agent to be licensed by the United States …