Belimumab: A step forward in the treatment of systemic lupus erythematosus

R Depascale, M Gatto, M Zen, F Saccon… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: Systemic Lupus Erythematosus (SLE) is a chronic B cell-mediated
autoimmune disease which can potentially involve several organs and systems. The …

Belimumab: A new targeted drug for systemic lupus erythematosus

C HE, F ZHANG - Medical Journal of Peking Union Medical …, 2020 - xhyxzz.pumch.cn
Systemic lupus erythematosus (SLE) is a complicated autoimmune disease characterized by
aberrant B cell activation. Belimumab is a human monoclonal antibody, which can reduce …

Real-world clinical outcomes in belimumab-treated US African American and Hispanic patients with systemic lupus erythematosus: a retrospective, observational …

CF Bell, J Chung, B Rubin - Rheumatology and Therapy, 2023 - Springer
Introduction This analysis aims to describe real-world clinical outcomes in US African
American and Hispanic patients with systemic lupus erythematosus (SLE) receiving …

Early disease and low baseline damage as predictors of response to belimumab in patients with systemic lupus erythematosus in a real‐life setting

M Gatto, F Saccon, M Zen, F Regola… - Arthritis & …, 2020 - Wiley Online Library
Objective To investigate predictors of response, remission, low disease activity, damage,
and drug discontinuation in patients with systemic lupus erythematosus (SLE) who were …

Potential and prognostic factor for belimumab-free remission in patients with systemic lupus erythematosus: a single-center retrospective analysis

T Nakai, S Fukui, Y Ikeda, H Shimizu, H Tamaki… - Clinical …, 2020 - Springer
Belimumab is an effective and safe treatment option for systemic lupus erythematosus (SLE).
However, data on treatment cessation are lacking. Thus, we investigated belimumab-free …

OP0048 Outcomes in Systemic Lupus Erythematous (SLE) Patients Treated with Belimumab in Clinical Practice Settings: Results from the Observe Study in Germany

A Schwarting, VB Koscielny, H Carnarius… - Annals of the …, 2014 - ard.bmj.com
Background Large-scale clinical trials have demonstrated clinical efficacy of belimumab in
SLE patients. Objectives This study examined the clinical outcomes associated with …

Risk of psychiatric disorders and all-cause mortality with belimumab therapy in patients with systemic lupus erythematosus: a meta-analysis of randomised controlled …

W Xie, H Huang, S Zhan, Z Zhang - Lupus Science & Medicine, 2021 - lupus.bmj.com
Objectives To evaluate the risk of psychiatric disorders and all-cause mortality associated
with belimumab therapy in patients with SLE. Methods A literature search of four electronic …

Belimumab versus anifrolumab in adults with systemic lupus erythematosus: an indirect comparison of clinical response at 52 weeks

B Neupane, P Shukla, M Slim, A Martin… - Lupus Science & …, 2023 - lupus.bmj.com
Objective To generate comparative efficacy evidence of belimumab versus anifrolumab in
SLE that can inform treatment practices. Methods The SLE Responder Index (SRI)-4 …

First real-world insights into belimumab use and outcomes in routine clinical care of systemic lupus erythematosus in Germany: results from the OBSErve Germany …

A Schwarting, JO Schroeder, T Alexander… - Rheumatology and …, 2016 - Springer
OBSErve Germany was the first observational study of belimumab as add-on treatment for
systemic lupus erythematosus (SLE) in routine clinical care in Germany, retrospectively …

Belimumab: targeted therapy for lupus

PK Chugh, BS Kalra - International Journal of Rheumatic …, 2013 - Wiley Online Library
Systemic lupus erythematosus (SLE), a complex autoimmune disease with multisystem
involvement, is characterised by recurring flares and remissions throughout the course of …