Impact of belimumab on patient-reported outcomes in systemic lupus erythematosus: review of clinical studies

E Bangert, L Wakani, M Merchant… - Patient Related …, 2019 - Taylor & Francis
Systemic lupus erythematosus (SLE) is a chronic autoimmune, multisystem rheumatic
disease with significant impact on health-related quality of life (HRQoL). Patient-reported …

Steroid-sparing effect of belimumab: results from a retrospective observational study of real-world data

K Worley, S Milligan, B Rubin - Lupus Science & Medicine, 2023 - lupus.bmj.com
Objective Comparison of oral corticosteroid (OCS) use in patients with SLE in a US
rheumatology network pre-and post-belimumab initiation. Methods This retrospective cohort …

An indirect comparison of intravenous and subcutaneous belimumab efficacy in patients with SLE and high disease activity

S Ramachandran, D Parks… - Journal of …, 2018 - becarispublishing.com
Aim: To compare the efficacy of intravenous (IV) and subcutaneous (SC) belimumab plus
standard therapy in patients with active, autoantibody-positive systemic lupus erythematosus …

[HTML][HTML] Belimumab and rituximab in systemic lupus erythematosus: a tale of two B cell-targeting agents

LM Wise, W Stohl - Frontiers in Medicine, 2020 - frontiersin.org
Given the centrality of B cells to systemic lupus erythematosus (SLE), it stands to reason that
a candidate therapeutic agent that targets B cells could be efficacious. Both rituximab, a …

Lupus clinical development: will belimumab's approval catalyse a new paradigm for SLE drug development?

L Runkel, J Stacey - Expert Opinion on Biological Therapy, 2014 - Taylor & Francis
Introduction: Systemic lupus erythematosus (SLE) is a diverse autoimmune disease affecting
many different organ systems. Although disease manifestations are varied across the lupus …

Efficacy and safety of subcutaneous belimumab in systemic lupus erythematosus: a fifty‐two–week randomized, double‐blind, placebo‐controlled study

W Stohl, A Schwarting, M Okada… - Arthritis & …, 2017 - Wiley Online Library
Objective To assess the efficacy and safety of subcutaneous (SC) belimumab in patients
with systemic lupus erythematosus (SLE). Methods Patients with moderate‐to‐severe SLE …

FRI0374 Outcomes in Systemic Lupus Erythematosus Patients with High Disease Activity Treated with Belimumab: 18 Month Results from the US Observe Study

CE Collins, M Dall'Era, C Macahilig, R Pappu… - Annals of the …, 2014 - ard.bmj.com
Background Certain baseline factors in the BLISS trials were associated with high disease
activity and identified as predictors of improved belimumab response. Objectives We …

[HTML][HTML] Real-world effectiveness of belimumab in patients with active lupus

Y Sumichika, S Yoshida, E Suzuki, K Saito… - Journal of Clinical …, 2023 - mdpi.com
This study evaluated the real-world effectiveness of belimumab (BLM) in the treatment of
systemic lupus erythematosus (SLE) patients with moderate to high disease activity. This …

Belimumab is approved by the FDA: what more do we need to know to optimize decision making?

DL Horowitz, R Furie - Current rheumatology reports, 2012 - Springer
The March 2011 approval of belimumab (Benlysta) by the US Food and Drug Administration
has left rheumatologists in a bit of a quandary regarding its use. It is officially intended for …

[HTML][HTML] Use of belimumab in real-world in Spain: a scoping review about characteristics of SLE patients

CR Escalera, ÁMZ Guisado, FJ Mateo… - Clinical …, 2022 - Springer
Background Belimumab was the first biological drug approved for Systemic Lupus
Erythematosus (SLE). There is not a review focusing on all real-life experience with …