Roles of myokines in exercise-induced improvement of neuropsychiatric function

S Kim, JY Choi, S Moon, DH Park, HB Kwak… - … -European Journal of …, 2019 - Springer
Exercise is a well-known non-pharmacological intervention to improve brain functions,
including cognition, memory, and motor coordination. Contraction of skeletal muscles during …

Exercise-induced myokines and their role in chronic diseases

BK Pedersen - Brain, behavior, and immunity, 2011 - Elsevier
Physical inactivity has recently been identified as a major and independent risk factor for the
development of dementia and cognitive decline. In addition to the effect of exercise with …

The role of exercise-induced myokines in regulating metabolism

JY Huh - Archives of pharmacal research, 2018 - Springer
Exercise has beneficial effects in ameliorating metabolic disorders, and a combined
therapeutic regimen of regular exercise and pharmaceutical treatment is often …

[HTML][HTML] Physical exercise-induced myokines and muscle-adipose tissue crosstalk: a review of current knowledge and the implications for health and metabolic …

LG Leal, MA Lopes, ML Batista Jr - Frontiers in physiology, 2018 - frontiersin.org
Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic
regimen of regular exercise and pharmaceutical treatment is often recommended for their …

Skeletal muscle is an endocrine organ

K Iizuka, T Machida, M Hirafuji - Journal of pharmacological sciences, 2014 - jstage.jst.go.jp
Skeletal muscle plays a key role in postural retention as well as locomotion for maintaining
the physical activities of human life. Skeletal muscle has a second role as an elaborate …

[HTML][HTML] Physical exercise-induced myokines in neurodegenerative diseases

B Lee, M Shin, Y Park, SY Won, KS Cho - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease
(PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are disorders …

[HTML][HTML] Exercise-induced myokines with therapeutic potential for muscle wasting

R Piccirillo - Frontiers in physiology, 2019 - frontiersin.org
Skeletal muscle is a highly vascularized tissue that can secrete proteins called myokines.
These muscle-secreted factors exert biological functions in muscle itself (autocrine effect) or …

Myokines mediate the cross talk between skeletal muscle and other organs

W Chen, L Wang, W You, T Shan - Journal of cellular …, 2021 - Wiley Online Library
Myokines are muscle‐derived cytokines and chemokines that act extensively on organs and
exert beneficial metabolic functions in the whole‐body through specific signal networks …

Physical activity and muscle–brain crosstalk

BK Pedersen - Nature Reviews Endocrinology, 2019 - nature.com
Neurological and mental illnesses account for a considerable proportion of the global
burden of disease. Exercise has many beneficial effects on brain health, contributing to …

Muscle–organ crosstalk: the emerging roles of myokines

MCK Severinsen, BK Pedersen - Endocrine reviews, 2020 - academic.oup.com
Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …