Resveratrol in management of bone and spinal cancers

G Chen, H Xia, Z Zhang, H Yu - Natural product research, 2019 - Taylor & Francis
Bone cancer is a malignant primary tumour of the bone with different typing, such as,
osteosarcoma, chondrosarcoma, Ewing's sarcoma and fibrosarcoma. Despite the clinical …

[HTML][HTML] Resveratrol is cytotoxic and acts synergistically with NF-κB inhibition in osteosarcoma MG-63 cells

N Xu, L Wang, S Fu, B Jiang - Archives of medical science: AMS, 2021 - ncbi.nlm.nih.gov
Results Our data suggested that Res blocks cell proliferation, migration, and invasion, and
activates apoptotic cell death in osteosarcoma MG-63 cells. We found that Res potentially …

[HTML][HTML] Antitumor activity of resveratrol against human osteosarcoma cells: A key role of Cx43 and Wnt/β-catenin signaling pathway

D Xie, GZ Zheng, P Xie, QH Zhang, FX Lin, B Chang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Osteosarcoma is a high-grade bone sarcoma with strong invasive ability. However,
treatment with traditional chemotherapeutic drugs is limited by low tolerability and side …

Multiple effects of resveratrol on osteosarcoma cell lines

A De Luca, D Bellavia, L Raimondi, V Carina, V Costa… - Pharmaceuticals, 2022 - mdpi.com
Osteosarcoma (OS) is the most common primary bone sarcoma affecting the life of pediatric
patients. The clinical treatment faces numerous difficulties, including the adverse effects of …

Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation

P Boissy, TL Andersen, BM Abdallah, M Kassem… - Cancer research, 2005 - AACR
Multiple myeloma is characterized by the accumulation of clonal malignant plasma cells in
the bone marrow, which stimulates bone destruction by osteoclasts and reduces bone …

A review of resveratrol as a potent chemoprotective and synergistic agent in cancer chemotherapy

Q Xiao, W Zhu, W Feng, SS Lee, AW Leung… - Frontiers in …, 2019 - frontiersin.org
Background: Cancer has become a major disease endangering human health around the
world. Conventional chemotherapy suffers from many side effects including pain …

[HTML][HTML] Resveratrol for cancer therapy: Challenges and future perspectives

B Ren, MXY Kwah, C Liu, Z Ma, MK Shanmugam… - Cancer letters, 2021 - Elsevier
Abstract Resveratrol (3, 4', 5-trihydroxy-trans-stilbene) has been expected to ameliorate
cancer and foster breakthroughs in cancer therapy. Despite thousands of preclinical studies …

Effects and mechanisms of resveratrol for prevention and management of cancers: An updated review

SX Wu, RG Xiong, SY Huang, DD Zhou… - Critical Reviews in …, 2023 - Taylor & Francis
Cancer is a severe public health problem. Resveratrol is a famous natural compound that
has various bioactivities, such as antioxidant, anti-inflammatory, antidiabetic and antiaging …

Resveratrol and its analogues: promising antitumor agents

HL Zhu - Anti-Cancer Agents in Medicinal Chemistry …, 2011 - ingentaconnect.com
Resveratrol, a well-know natural product and a major component in grape, has attracted
considerable attention as one of the most promising cancer during the past decade. Many …

Resveratrol: potential as anticancer agent

JK Aluyen, QN Ton, T Tran, AE Yang… - Journal of dietary …, 2012 - Taylor & Francis
Background: Cancer is one of the leading causes of deaths in the world. Current
chemotherapeutic agents are associated with serious side effects in patients therefore …