Virulence Characteristics and an Action Mode of Antibiotic Resistance in Multidrug-Resistant Pseudomonas aeruginosa

W Hwang, SS Yoon - Scientific reports, 2019 - nature.com
Pseudomonas aeruginosa displays intrinsic resistance to many antibiotics and known to
acquire actively genetic mutations for further resistance. In this study, we attempted to …

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

What It Takes to Be a Pseudomonas aeruginosa? The Core Genome of the Opportunistic Pathogen Updated

B Valot, C Guyeux, JY Rolland, K Mazouzi, X Bertrand… - PloS one, 2015 - journals.plos.org
Pseudomonas aeruginosa is an opportunistic bacterial pathogen able to thrive in highly
diverse ecological niches and to infect compromised patients. Its genome exhibits a mosaic …

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients

RL Marvig, LM Sommer, L Jelsbak, S Molin… - Future …, 2015 - Future Medicine
The opportunistic pathogen Pseudomonas aeruginosa causes chronic airway infections in
patients with cystic fibrosis (CF), and it is directly associated with the morbidity and mortality …

Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen

KZ Abram, SR Jun, Z Udaondo - Pseudomonas aeruginosa: Biology …, 2022 - Springer
In this chapter, we leverage a novel approach to assess the seamless population structure of
Pseudomonas aeruginosa, using the full repertoire of genomes sequenced to date …

The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity

L Freschi, AT Vincent, J Jeukens… - Genome biology and …, 2019 - academic.oup.com
The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …

Genome Analysis of Pseudomonas aeruginosa Strains from Chronically Infected Patients with High Levels of Persister Formation

AA Baiomy, FE Serry, AA Kadry, G Yahya, S Doijad… - Pathogens, 2023 - mdpi.com
The appearance of persister cells with low metabolic rates are key factors leading to
antibiotic treatment failure. Such persisters are multidrug tolerant and play a key role in the …

Genomic characterization of carbapenem-non-susceptible Pseudomonas aeruginosa in Singapore

JQM Teo, CY Tang, JC Lim, SJY Lee… - Emerging Microbes & …, 2021 - Taylor & Francis
Pseudomonas aeruginosa is a clinically important pathogen implicated in many hospital-
acquired infections. Its propensity to acquire broad-spectrum resistance has earned the …

Development and validation of a PCR assay to detect the prairie epidemic strain of Pseudomonas aeruginosa from patients with cystic fibrosis

M Workentine, A Poonja, B Waddell… - Journal of Clinical …, 2016 - Am Soc Microbiol
The monitoring of epidemic Pseudomonas aeruginosa is important for cystic fibrosis (CF)
infection control. The prairie epidemic strain (PES) is common in western Canadian CF …

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

L Freschi, J Jeukens, I Kukavica-Ibrulj, B Boyle… - Frontiers in …, 2015 - frontiersin.org
The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …