The distributed genome hypothesis (DGH) states that each strain within a bacterial species
receives a unique distribution of genes from a population-based supragenome that is many …

Pseudomonas aeruginosa is an opportunistic pathogen that causes difficult-to-treat
infections. Two well-studied divergent P. aeruginosa strain types, PAO1 and PA14, have …

Background Pseudomonas aeruginosa is an opportunistic pathogen with a high incidence
of hospital infections that represents a threat to immune compromised patients. Genomic …

Objectives Pseudomonas aeruginosa is a leading cause of community-and hospital-
acquired infections. Successful treatment is hampered by its remarkable ability to rapidly …

We have recently characterised the epidemiology of P. aeruginosa blood stream infection
(BSI) in a large retrospective multicentre cohort study [1]. Utilising corresponding patient BSI …

Pseudomonas aeruginosa is an opportunistic pathogen that often causes nosocomial
infections resistant to treatment. Rates of antimicrobial resistance (AMR) are increasing, as …

The ever-increasing prevalence of infections produced by multidrug-resistant or extensively
drug-resistant Pseudomonas aeruginosa is commonly linked to a limited number of aptly …

Pseudomonas aeruginosa is an opportunistic human pathogen that frequently causes
health care-associated infections (HAIs). Due to its metabolic diversity and ability to form …

Background Bacteria employ a variety of adaptation strategies during the course of chronic
infections. Understanding bacterial adaptation can facilitate the identification of novel drug …

The first Pseudomonas genome was sequenced in 2000, and at 6.3 million base pairs, it
was, at the time, the largest bacterial genome ever sequenced (Stover et al., 2000). Not …