Appropriate immune responses require a fine balance between immune activation and
attenuation. NLRC3, a non-inflammasome-forming member of the NLR innate immune …

Members of the nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR)
family are quickly emerging as critical regulators of innate and adaptive immune responses …

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating …

Stringent control of the NF-κB and type I interferon signaling pathways is critical to effective
host immune responses, yet the molecular mechanisms that negatively regulate these …

Nucleotide-binding domain and leucine rich repeat containing gene family receptors (NLRs)
are cytosolic proteins that respond to a variety of pathogen and host components to induce …

Intracellular NOD-like receptor (NLR) proteins are believed to play important roles in innate
immune detection or immune regulation, but only a few NLR proteins are functionally …

NOD-like receptors (NLRs) are a family of intracellular proteins that play critical roles in
innate immunity against microbial infection. NLRC5, the largest member of the NLR family …

Nod-like receptors (NLRs) are intracellular sensors that respond to a variety of pathogen
and intracellular danger signals to induce innate immune responses. NLRC5 has recently …

Nod-like receptors (NLRs) are intracellular sentinel proteins that are implicated in the
detection of microbes and danger signals, thereby controlling several key innate immune …

Innate immune cells rely on pathogen recognition receptors such as the nucleotide-binding
and oligomerization domain (NOD)-like receptor (NLR) family to mount an appropriate …