Evaluation of the effectiveness of cytisine for the treatment of smoking cessation: a systematic review and meta‐analysis

O De Santi, M Orellana, CA Di Niro, V Greco - Addiction, 2024 - Wiley Online Library
Background and aims Smoking is considered the main cause of preventable death world‐
wide. This study aimed to review the efficacy and safety of cytisine for smoking cessation …

Cytisine for smoking cessation: a systematic review and meta-analysis

S Ofori, C Lu, OO Olasupo, BB Dennis… - Drug and Alcohol …, 2023 - Elsevier
Background Cytisine is a smoking cessation medication. This systematic review
incorporates recently published randomized controlled trials (RCTs) to provide an updated …

Efficacy of cytisine in helping smokers quit: systematic review and meta-analysis

P Hajek, H McRobbie, K Myers - Thorax, 2013 - thorax.bmj.com
Background A recent rigorous study has shown that cytisine, a low-cost drug, is effective for
smoking cessation. A number of earlier studies exist, mostly from former communist …

Cytisine for nicotine addiction treatment: a review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation

P Tutka, D Vinnikov, RJ Courtney, NL Benowitz - Addiction, 2019 - Wiley Online Library
Aims To review cytisine's history of use, pre‐clinical evidence, clinical pharmacokinetics,
efficacy, adverse reactions (ARs) and safety for smoking cessation. Methods A synoptic …

[HTML][HTML] Study protocol for a non-inferiority trial of cytisine versus nicotine replacement therapy in people motivated to stop smoking

N Walker, C Howe, C Bullen, H McRobbie, M Glover… - BMC Public Health, 2011 - Springer
Background Smokers need effective support to maximise the chances of successful quit
attempts. Current smoking cessation medications, such as nicotine replacement therapy …

[HTML][HTML] Placebo-controlled trial of cytisine for smoking cessation

R West, W Zatonski, M Cedzynska… - … England Journal of …, 2011 - Mass Medical Soc
Background Cytisine, a partial agonist that binds with high affinity to the α4β2 nicotinic
acetylcholine receptor, is a low-cost treatment that may be effective in aiding smoking …

Effect of cytisine vs varenicline on smoking cessation: a randomized clinical trial

RJ Courtney, H McRobbie, P Tutka, NA Weaver… - Jama, 2021 - jamanetwork.com
Importance Cytisine is more effective than placebo and nicotine replacement therapy for
smoking cessation. However, cytisine has not been tested against the most effective …

[HTML][HTML] Cytisine versus nicotine for smoking cessation

N Walker, C Howe, M Glover… - … England Journal of …, 2014 - Mass Medical Soc
Background Placebo-controlled trials indicate that cytisine, a partial agonist that binds the
nicotinic acetylcholine receptor and is used for smoking cessation, almost doubles the …

The effectiveness, safety and cost‐effectiveness of cytisine versus varenicline for smoking cessation in an Australian population: a study protocol for a randomized …

D Thomas, M Farrell, H McRobbie, P Tutka, D Petrie… - …, 2019 - Wiley Online Library
Background and aims Smoking cessation medications are effective, but often underutilized
because of costs and side effects. Cytisine is a plant‐based smoking cessation medication …

Cytisine for smoking cessation

T Karnieg, X Wang - Cmaj, 2018 - Can Med Assoc
1. Rigotti NA. Cytisine—a tobacco treatment hiding in plain sight. N Engl J Med 2014; 371:
2429-30. 2. Jeong SH, Newcombe D, Sheridan J, et al. Pharmacokinetics of cytisine, an α4 …