The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

[HTML][HTML] The effect of aging on resting state connectivity of predefined networks in the brain

E Varangis, CG Habeck, QR Razlighi… - Frontiers in aging …, 2019 - frontiersin.org
Recent studies have found a deleterious effect of age on a wide variety of measures of
functional connectivity, and some hints at a relationship between connectivity at rest and …

Resting-state networks in the course of aging—differential insights from studies across the lifespan vs. amongst the old

C Jockwitz, S Caspers - Pflügers Archiv-European Journal of Physiology, 2021 - Springer
Resting-state functional connectivity (RSFC) has widely been used to examine
reorganization of functional brain networks during normal aging. The extraction of …

Influence of age and cognitive performance on resting-state brain networks of older adults in a population-based cohort

C Jockwitz, S Caspers, S Lux, SB Eickhoff, K Jütten… - Cortex, 2017 - Elsevier
Aging leads to global changes in brain structure and cognitive performance, with
reorganization of functional brain networks. Importantly, these age-related changes show …

[HTML][HTML] Aging relates to a disproportionately weaker functional architecture of brain networks during rest and task states

C Hughes, J Faskowitz, BS Cassidy, O Sporns… - NeuroImage, 2020 - Elsevier
Functional connectivity–the co-activation of brain regions–forms the basis of the brain's
functional architecture. Often measured during resting-state (ie, in a task-free setting) …

Age‐related changes in resting‐state networks of a large sample size of healthy elderly

CC Huang, WJ Hsieh, PL Lee, LN Peng… - CNS Neuroscience …, 2015 - Wiley Online Library
Aims Population aging is burdening the society globally, and the evaluation of functional
networks is the key toward understanding cognitive changes in normal aging. However, the …

Longitudinal changes in the cerebral cortex functional organization of healthy elderly

JSX Chong, KK Ng, J Tandi, C Wang… - Journal of …, 2019 - Soc Neuroscience
Healthy aging is accompanied by disruptions in the functional modular organization of the
human brain. Cross-sectional studies have shown age-related reductions in the functional …

The independent influences of age and education on functional brain networks and cognition in healthy older adults

A Perry, W Wen, NA Kochan, A Thalamuthu… - Human Brain …, 2017 - Wiley Online Library
Healthy aging is accompanied by a constellation of changes in cognitive processes and
alterations in functional brain networks. The relationships between brain networks and …

Associations between dynamic functional connectivity and age, metabolic risk, and cognitive performance

RP Viviano, N Raz, P Yuan, JS Damoiseaux - Neurobiology of aging, 2017 - Elsevier
Advanced age is associated with reduced within-network functional connectivity, particularly
within the default mode network. Most studies to date have examined age differences in …

[HTML][HTML] Functional network reorganization in older adults: Graph-theoretical analyses of age, cognition and sex

J Stumme, C Jockwitz, F Hoffstaedter, K Amunts… - NeuroImage, 2020 - Elsevier
Healthy aging has been associated with a decrease in functional network specialization.
Importantly, variability of alterations of functional connectivity is especially high across older …