Biological Activity of fac-[Re(CO)3(phen)(aspirin)], fac-[Re(CO)3(phen)(indomethacin)] and Their Original Counterparts against Ishikawa and HEC-1A Endometrial …

O Kuźmycz, A Kowalczyk, P Stączek - International Journal of Molecular …, 2022 - mdpi.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) are inhibitors of cyclooxygenase enzyme
(COX) and were found to have positive effects in reducing the risk of developing …

[PDF][PDF] Nonsteroidal anti-inflammatory drugs (NSAIDs) derivatives with anti-cancer activity

T Elsaman, MM Ali - American Journal of Research …, 2016 - researchgate.net
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a diverse class of drugs commonly used
for the treatment of inflammatory conditions, have been found to be highly effective in …

[HTML][HTML] NSAID's and selectively COX-2 inhibitors as potential chemoprotective agents against cancer: 1st Cancer Update

N Kumar, S Drabu, SC Mondal - Arabian Journal of Chemistry, 2013 - Elsevier
Non-steroidal anti-inflammatory drugs act by inhibiting cyclooxigenase enzyme in the
plasma membrane predominantly. Nowadays many researchers have observed a great …

Design, synthesis and structure–activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs

S Hayashi, N Ueno, A Murase… - Journal of enzyme …, 2014 - Taylor & Francis
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-
steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used …

[HTML][HTML] In vitro cytotoxic evaluation of some synthesized COX-2 inhibitor derivatives against a panel of human cancer cell lines

H Sadeghi-Aliabadi, M Aliasgharluo… - Research in …, 2013 - ncbi.nlm.nih.gov
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) developed as a selective
inhibitor of cyclooxygenase-2 (COX-2) for the treatment of rheumatoid arthritis disease …

Anticancer and antimicrobial activities of naproxen and naproxen derivatives

Mİ Han, ŞG Küçükgüzel - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
This review explains the effects of naproxen and the naproxen moiety in important biological
activities. Naproxen, 2-(6-methoxynaphthalen-2-yl) propionic acid, is one of the most utilized …

New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects

T Güngör, A Ozleyen, YB Yılmaz, P Siyah, M Ay… - European Journal of …, 2021 - Elsevier
Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and
characterized by several spectroscopic techniques and primarily investigated for their …

Prospects of NSAIDs administration as double-edged agents against endometrial cancer and pathological species of the uterine microbiome

O Kuźmycz, P Stączek - Cancer biology & therapy, 2020 - Taylor & Francis
Many types of cancers, including endometrial cancer, were found to have cyclooxygenase-2
(COX-2) overexpression. Because this enzyme belongs to the group of pro-inflammatory …

Effects of a cyclooxygenase-1-selective inhibitor in a mouse model of ovarian cancer, administered alone or in combination with ibuprofen, a nonselective …

W Li, R Xu, Z Lin, G Zhuo, H Zhang - Medical oncology, 2009 - Springer
Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to be potent inhibitors of the
cyclooxygenases. The present study was designed to investigate the effects of a …

Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells

Ö Özdemir, L Marinelli, I Cacciatore… - … für Naturforschung C, 2021 - degruyter.com
Several epidemiologic, clinical and experimental reports indicate that nonsteroidal anti-
inflammatory drugs (NSAIDs) could have a potential as anticancer agents. The aim of this …