[HTML][HTML] Superantigen recognition and interactions: functions, mechanisms and applications
AM Deacy, SKE Gan, JP Derrick - Frontiers in Immunology, 2021 - frontiersin.org
Superantigens are unconventional antigens which recognise immune receptors outside
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …
Microbial superantigens: from structure to function
AC Papageorgiou, KR Acharya - Trends in microbiology, 2000 - cell.com
Superantigens are highly potent immune stimulators with a unique ability to interact
simultaneously with MHC class II molecules and T cell receptors, forming a trimolecular …
simultaneously with MHC class II molecules and T cell receptors, forming a trimolecular …
[HTML][HTML] Superantigens as immunomodulators: recent structural insights
AC Papageorgiou, KR Acharya - Structure, 1997 - cell.com
Superantigens interact with major histocompatibility complex (MHC) class II molecules and T-
cell receptors (TcRs) forming a trimolecular complex which is able to induce proliferation …
cell receptors (TcRs) forming a trimolecular complex which is able to induce proliferation …
Superantigens–powerful modifiers of the immune system
Superantigens are powerful microbial toxins that activate the immune system by binding to
class II major histocompatibility complex and T-cell receptor molecules. They cause a …
class II major histocompatibility complex and T-cell receptor molecules. They cause a …
How do T-cell receptors, MHC molecules and superantigens get together?
DL Woodland, MA Blackman - Immunology today, 1993 - cell.com
The current model of superantigen activity assumes that the superantigen simultaneously
binds to both the MHC molecule on the presenting cell and the V~ element of the TCR …
binds to both the MHC molecule on the presenting cell and the V~ element of the TCR …
Superantigens: structure-function relationships
MD Baker, KR Acharya - International Journal of Medical Microbiology, 2004 - Elsevier
Superantigens are a class of highly potent immuno-stimulatory molecules produced by
Staphylococcus aureus and Streptococcus pyogenes. These toxins possess the unique …
Staphylococcus aureus and Streptococcus pyogenes. These toxins possess the unique …
Interplay between superantigens and the immune system
MJ Irwin, NRJ Gascoigne - Journal of leukocyte biology, 1993 - Wiley Online Library
Superantigens interact with the immune system by binding to major histocompatibility
complex (MHG) class II proteins and activating T cells through the variable region of the T …
complex (MHG) class II proteins and activating T cells through the variable region of the T …
Superantigens of Gram-positive bacteria: structure—function analyses and their implications for biological activity
M Kotb - Current Opinion in Microbiology, 1998 - Elsevier
Just as we thought that we know everything about superantigens, new molecular and
structural studies indicate that we have only just begun to unravel the secrets of these …
structural studies indicate that we have only just begun to unravel the secrets of these …
B-cell superantigens
GJ Silverman - Immunology today, 1997 - cell.com
Superantigens (SAgs) are characterized by their ability to interact with T-and B-cell antigen
(Ag) receptors outside of the classical Ag-binding groove. Here, Gress Silverman discusses …
(Ag) receptors outside of the classical Ag-binding groove. Here, Gress Silverman discusses …
Superantigens: structure and relevance to human disease
HM Johnson, BA Torres… - Proceedings of the Society …, 1996 - journals.sagepub.com
Superantigens are a class of immunostimulatory molecules produced by bacterla and
viruses. Their potent immune effects are due to their unique ability to bind to the major …
viruses. Their potent immune effects are due to their unique ability to bind to the major …