The importance of co‐delivery of nanoparticle‐siRNA and anticancer agents in cancer therapy
N Khelghati… - Chemical Biology & …, 2021 - Wiley Online Library
According to global statistics, cancer is the second leading cause of death worldwide.
Because of the heterogeneity of cancer, single‐drug therapy has many limitations due to low …
Because of the heterogeneity of cancer, single‐drug therapy has many limitations due to low …
Nanoparticle‐mediated siRNA delivery and multifunctional modification strategies for effective cancer therapy
M Chen, C Dong, S Shi - Advanced Materials Technologies, 2021 - Wiley Online Library
RNA interference (RNAi), which can inhibit the expression or transcription of specific genes,
is considered to be a revolutionary tool for mediating gene therapy. Small interfering RNA …
is considered to be a revolutionary tool for mediating gene therapy. Small interfering RNA …
Tumor‐targeting multifunctional nanoparticles for siRNA delivery: Recent advances in cancer therapy
RNA interference (RNAi) is a naturally occurring regulatory process that controls
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …
Nanoparticle-mediated co-delivery of chemotherapeutic agent and siRNA for combination cancer therapy
Introduction: Cancer is the leading cause of death worldwide. Current cancer treatments in
the clinic mainly include chemotherapy, radiotherapy and surgery, with chemotherapy being …
the clinic mainly include chemotherapy, radiotherapy and surgery, with chemotherapy being …
Nanoparticle-mediated delivery of siRNA for effective lung cancer therapy
YD Kim, TE Park, B Singh, S Maharjan, YJ Choi… - …, 2015 - Taylor & Francis
Lung cancer is one of the most lethal diseases worldwide, and the survival rate is less than
15% even after the treatment. Unfortunately, chemotherapeutic treatments for lung cancer …
15% even after the treatment. Unfortunately, chemotherapeutic treatments for lung cancer …
Recent advancements in the design of nanodelivery systems of siRNA for cancer therapy
RNA interference (RNAi) has increased the possibility of restoring RNA drug targets for
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …
Insights on prospects of nano-siRNA based approaches in treatment of Cancer
siRNA interference, commonly referred to as gene silence, is a biological mechanism that
inhibits gene expression in disorders such as cancer. It may enhance the precision, efficacy …
inhibits gene expression in disorders such as cancer. It may enhance the precision, efficacy …
[HTML][HTML] Nano-formulated siRNA-based therapeutic approaches for cancer therapy
D Jain, SK Prajapati, A Jain, R Singhal - Nano Trends, 2023 - Elsevier
RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
Nanoparticle-based combination therapy for cancer treatment
In recent years, combination of different types of therapies using nanoparticles has emerged
as an advanced strategy for cancer treatment. Most of all, combination of chemotherapeutic …
as an advanced strategy for cancer treatment. Most of all, combination of chemotherapeutic …
Nanoparticle‐mediated siRNA delivery systems for cancer therapy
The small interfering RNA (siRNA)‐based therapeutics have raised great attention since the
first RNA interference (RNAi)‐derived drug, patisiran, was approved by the US Food and …
first RNA interference (RNAi)‐derived drug, patisiran, was approved by the US Food and …