Impact of TRP channels in Oral pathology and therapeutic targeting options: a narrative review

E Evangeliou, G Plemmenos… - Current Topics in …, 2023 - ingentaconnect.com
Background: Transient Receptor Potential (TRP) channels are non-selective Ca2+
permeable channels with a wide and dynamic involvement in the perception of …

[HTML][HTML] The role of transient receptor potential (TRP) channels in the transduction of dental pain

MZ Hossain, MM Bakri, F Yahya, H Ando… - International journal of …, 2019 - mdpi.com
Dental pain is a common health problem that negatively impacts the activities of daily living.
Dentine hypersensitivity and pulpitis-associated pain are among the most common types of …

Epithelial TRPV1 channels: expression, function, and pathogenicity in the oral cavity

N Takahashi, T Tsuzuno, S Mineo… - Journal of Oral …, 2020 - Elsevier
Background The oral cavity serves as an entrance to the body and is therefore exposed to
various exogenous stimuli, including mechanical forces, chemical agents, and bacterial …

[HTML][HTML] TRP Channels in Cancer: Therapeutic Opportunities and Research Strategies

J Xu, Z Wang, Y Niu, Y Tang, Y Wang, J Huang… - Pharmacological …, 2024 - Elsevier
The influence of gut microbiota on transient receptor potential (TRP) channels has been
identified as an important element in developing gastrointestinal conditions, yet its …

TRP channels in dental pain

G Chung, SB Oh - The Open Pain Journal, 2013 - benthamopen.com
Despite the high incidence of dental pain, the mechanism underlying its generation is mostly
unknown. Functional expression of temperature-sensitive transient receptor potential …

Role of TRP channels in pain: an overview

A Szallasi - Vanilloid Receptor TRPV1 in Drug Discovery …, 2010 - Wiley Online Library
Despite the investment of significant resources by the pharmaceutical industry to identify
novel analgesic drugs, chronic pain, which is most commonly defined as pain lasting longer …

[HTML][HTML] TRP channels as molecular targets to relieve cancer pain

M Duitama, Y Moreno, SP Santander, Z Casas… - Biomolecules, 2021 - mdpi.com
Transient receptor potential (TRP) channels are critical receptors in the transduction of
nociceptive stimuli. The microenvironment of diverse types of cancer releases substances …

Multiple roles of transient receptor potential (TRP) channels in inflammatory conditions and current status of drug development

O Radresa, M Paré, JS Albert - Current Topics in Medicinal …, 2013 - ingentaconnect.com
During inflammation, several Transient Receptor Potential (TRP) channels are directly or
indirectly activated by inflammatory signaling molecules and microenvironmental changes …

Localization of TRP channels in healthy oral mucosa from human donors

Y Moayedi, S Michlig, M Park, A Koch, EA Lumpkin - eneuro, 2022 - eneuro.org
The oral cavity is exposed to a remarkable range of noxious and innocuous conditions,
including temperature fluctuations, mechanical forces, inflammation, and environmental and …

Oral Epithelial Cells are Activated via TRP Channels

B Wang, A Danjo, H Kajiya, K Okabe… - Journal of dental …, 2011 - journals.sagepub.com
Transient receptor potential (TRP) ion channels are critical contributors to the perception of
various environmental stimuli. Although the oral cavity is the access point for various food …