The transmembrane domain of BST-2 determines its sensitivity to down-modulation by human immunodeficiency virus type 1 Vpu
L Rong, J Zhang, J Lu, Q Pan, RP Lorgeoux… - Journal of …, 2009 - Am Soc Microbiol
Bone marrow stromal cell antigen 2 (BST-2, also known as tetherin) restricts the production
of a number of enveloped viruses by blocking virus release from the cell surface. This …
of a number of enveloped viruses by blocking virus release from the cell surface. This …
The Ebola virus glycoprotein and HIV-1 Vpu employ different strategies to counteract the antiviral factor tetherin
A Kühl, C Banning, A Marzi, J Votteler… - The Journal of …, 2011 - academic.oup.com
The antiviral protein tetherin/BST2/CD317/HM1. 24 restricts cellular egress of human
immunodeficiency virus (HIV) and of particles mimicking the Ebola virus (EBOV), a …
immunodeficiency virus (HIV) and of particles mimicking the Ebola virus (EBOV), a …
Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue
M Schindler, D Rajan, C Banning, P Wimmer… - Retrovirology, 2010 - Springer
Background The human immunodeficiency virus type 1 (HIV-1) Vpu protein degrades CD4
and counteracts a restriction factor termed tetherin (CD317; Bst-2) to enhance virion release …
and counteracts a restriction factor termed tetherin (CD317; Bst-2) to enhance virion release …
Filamin A is involved in HIV-1 Vpu-mediated evasion of host restriction by modulating tetherin expression
D Dotson, EA Woodruff, F Villalta, X Dong - Journal of Biological Chemistry, 2016 - ASBMB
Tetherin, also known as bone marrow stromal antigen 2 (BST-2), inhibits the release of a
wide range of enveloped viruses, including human immunodeficiency virus, type 1 (HIV-1) …
wide range of enveloped viruses, including human immunodeficiency virus, type 1 (HIV-1) …
BST2/Tetherin enhances entry of human cytomegalovirus
K Viswanathan, MS Smith, D Malouli… - PLoS …, 2011 - journals.plos.org
Interferon-induced BST2/Tetherin prevents budding of vpu-deficient HIV-1 by tethering
mature viral particles to the plasma membrane. BST2 also inhibits release of other …
mature viral particles to the plasma membrane. BST2 also inhibits release of other …
Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein
RL Kaletsky, JR Francica… - Proceedings of the …, 2009 - National Acad Sciences
Mammalian cells employ numerous innate cellular mechanisms to inhibit viral replication
and spread. Tetherin, also known as Bst-2 or CD317, is a recently identified, IFN-induced …
and spread. Tetherin, also known as Bst-2 or CD317, is a recently identified, IFN-induced …
[HTML][HTML] Vpu-mediated tetherin antagonism of ongoing HIV-1 infection in CD4+ T-cells is not directly related to the extent of tetherin cell surface downmodulation
Tetherin is a host cell restriction factor that acts against HIV-1 and other enveloped viruses.
The antiviral activity of tetherin is antagonized by the HIV-1 protein Vpu, that downregulates …
The antiviral activity of tetherin is antagonized by the HIV-1 protein Vpu, that downregulates …
Increased BST2 expression during simian immunodeficiency virus infection is not a determinant of disease progression in rhesus monkeys
B Mussil, A Javed, K Töpfer, U Sauermann, S Sopper - Retrovirology, 2015 - Springer
Background Bone marrow stromal cell antigen 2 (BST2), also known as tetherin, HM1. 24 or
CD317 represents a type 2 integral membrane protein, which has been described to restrict …
CD317 represents a type 2 integral membrane protein, which has been described to restrict …
Structural basis for the antiviral activity of BST-2/tetherin and its viral antagonism
JF Arias, Y Iwabu, K Tokunaga - Frontiers in microbiology, 2011 - frontiersin.org
The interferon-inducible host restriction factor bone marrow stromal antigen 2 (BST-
2/tetherin) blocks the release of HIV-1 and other enveloped viruses. In turn, these viruses …
2/tetherin) blocks the release of HIV-1 and other enveloped viruses. In turn, these viruses …
Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a βTrCP-dependent mechanism
JL Douglas, K Viswanathan, MN McCarroll… - Journal of …, 2009 - Am Soc Microbiol
The primary roles attributed to the human immunodeficiency virus type 1 (HIV-1) Vpu protein
are the degradation of the viral receptor CD4 and the enhancement of virion release. With …
are the degradation of the viral receptor CD4 and the enhancement of virion release. With …