[HTML][HTML] Differential Sensitivity to Plasmodium yoelii Infection in C57BL/6 Mice Impacts Gut-Liver Axis Homeostasis
JE Denny, JB Powers, HF Castro, J Zhang… - Scientific reports, 2019 - nature.com
Experimental models of malaria have shown that infection with specific Plasmodium species
in certain mouse strains can transiently modulate gut microbiota and cause intestinal …
in certain mouse strains can transiently modulate gut microbiota and cause intestinal …
Composition of the gut microbiota modulates the severity of malaria
NF Villarino, GR LeCleir, JE Denny… - Proceedings of the …, 2016 - National Acad Sciences
Plasmodium infections result in clinical presentations that range from asymptomatic to
severe malaria, resulting in∼ 1 million deaths annually. Despite this toll on humanity, the …
severe malaria, resulting in∼ 1 million deaths annually. Despite this toll on humanity, the …
[HTML][HTML] Functional Characteristics of the Gut Microbiome in C57BL/6 Mice Differentially Susceptible to Plasmodium yoelii
JMA Stough, SP Dearth, JE Denny… - Frontiers in …, 2016 - frontiersin.org
C57BL/6 mice are widely used for in vivo studies of immune function and metabolism in
mammals. In a previous study, it was observed that when C57BL/6 mice purchased from …
mammals. In a previous study, it was observed that when C57BL/6 mice purchased from …
[HTML][HTML] The dynamic landscape of parasitemia dependent intestinal microbiota shifting and the correlated gut transcriptome during Plasmodium yoelii infection
Z Yawen, C Xiangyun, L Binyou, Y Xingchen… - Microbiological …, 2022 - Elsevier
Malaria, caused by Plasmodium, is a global life-threatening infectious disease. However, the
dynamic interactions between intestinal microbiota and host immunity during the infections …
dynamic interactions between intestinal microbiota and host immunity during the infections …
[HTML][HTML] Genome-wide liver transcriptomic profiling of a malaria mouse model reveals disturbed immune and metabolic responses
X Hu, J Zhao, J Zhao, E Yang, M Jia - Parasites & Vectors, 2023 - Springer
Background The liver is responsible for a range of functions in vertebrates, such as
metabolism and immunity. In malaria, the liver plays a crucial role in the interaction between …
metabolism and immunity. In malaria, the liver plays a crucial role in the interaction between …
[HTML][HTML] Intestinal injury and the gut microbiota in patients with Plasmodium falciparum malaria
N Sriboonvorakul, K Chotivanich… - PLoS …, 2023 - journals.plos.org
The pathophysiology of severe falciparum malaria involves a complex interaction between
the host, parasite, and gut microbes. In this review, we focus on understanding parasite …
the host, parasite, and gut microbes. In this review, we focus on understanding parasite …
[PDF][PDF] Gut microbiota composition modulates the magnitude and quality of germinal centers during Plasmodium infections
ML Waide, R Polidoro, WL Powell, JE Denny, J Kos… - Cell reports, 2020 - cell.com
Gut microbiota composition is associated with human and rodent Plasmodium infections, yet
the mechanism by which gut microbiota affects the severity of malaria remains unknown …
the mechanism by which gut microbiota affects the severity of malaria remains unknown …
[HTML][HTML] Malaria disrupts the rhesus macaque gut microbiome
DN Farinella, S Kaur, VL Tran… - Frontiers in Cellular …, 2023 - frontiersin.org
Previous studies have suggested that a relationship exists between severity and
transmissibility of malaria and variations in the gut microbiome, yet only limited information …
transmissibility of malaria and variations in the gut microbiome, yet only limited information …
[HTML][HTML] Inflammation-associated alterations to the intestinal microbiota reduce colonization resistance against non-typhoidal Salmonella during concurrent malaria …
Childhood malaria is a risk factor for disseminated infections with non-typhoidal Salmonella
(NTS) in sub-Saharan Africa. While hemolytic anemia and an altered cytokine environment …
(NTS) in sub-Saharan Africa. While hemolytic anemia and an altered cytokine environment …
[PDF][PDF] Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
ÂF Chora, S Marques, JL Gonçalves, P Lima… - Immunity, 2023 - cell.com
Plasmodium replicates within the liver prior to reaching the bloodstream and infecting red
blood cells. Because clinical manifestations of malaria only arise during the blood stage of …
blood cells. Because clinical manifestations of malaria only arise during the blood stage of …