Mitochondria and oxidative stress play important roles in neuronal cell death associated with
cerebral ischemia. Elevated level of reactive oxygen species (ROS) and mitochondrial …

Abstract Pinocembrin (PB; 5, 7-dihydroxyflavanone) is found in propolis and exhibits
antioxidant activity in several experimental models. The antioxidant capacity of PB is …

Mitochondrial dysfunction is part of the mechanism of several human diseases. This
negative circumstance may be induced by certain toxicants, as methylglyoxal (MG). MG is a …

Oxidative stress can induce cytotoxicity in neurons, which plays an important role in the
etiology of neuronal damage and degeneration. This study sought to determine the cellular …

Background: Over the last decades, a large amount of literature regarding lipid peroxidation
has shown its important role in cell biology and human health. Previous studies have shown …

There is an increasing evidence that oxidative stress is implicated in the processes of
inflammation and carcinogenesis. It has been shown that kahweol and cafestol, coffee …

Excessive exposure to manganese in the environment or workplace is strongly linked to
neurodegeneration and cognitive impairment, but the precise pathogenic mechanism and …

Oxidative stress has been implicated in several pathologies associated with degenerative
processes. Mitochondria are involved in cell death by necrosis or apoptosis due to a large …

Abstract Objective: To investigate whether (+)-catechin, a strong antioxidant, can prevent
methylglyoxal (MGO)-induced cytotoxicity and its mechanism. Methods: Cytotoxicity …

Mitochondriotropic antioxidants (MC3, MC6. 2, MC4 and MC7. 2) based on dietary
antioxidants and analogs (caffeic, hydrocaffeic, trihydroxyphenylpropanoic and …