[HTML][HTML] Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents

S Hashem, TA Ali, S Akhtar, S Nisar, G Sageena… - Biomedicine & …, 2022 - Elsevier
Cancer is one of the leading causes of death and significantly burdens the healthcare
system. Due to its prevalence, there is undoubtedly an unmet need to discover novel …

Natural products: An upcoming therapeutic approach to cancer

S Dutta, S Mahalanobish, S Saha, S Ghosh… - Food and Chemical …, 2019 - Elsevier
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

Back to basics: how natural products can provide the basis for new therapeutics

A Deorukhkar, S Krishnan, G Sethi… - Expert opinion on …, 2007 - Taylor & Francis
Phytochemicals have potent antitumor properties and have provided multiple active
compounds in the past. Although there is an increasing focus on 'designer'targeted …

The role of natural products and their multitargeted approach to treat solid cancer

N Muhammad, D Usmani, M Tarique, H Naz, M Ashraf… - Cells, 2022 - mdpi.com
Natural products play a critical role in the discovery and development of numerous drugs for
the treatment of various types of cancer. These phytochemicals have demonstrated anti …

Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products

MM Rahman, MT Sarker, MA Alam Tumpa… - Frontiers in …, 2022 - frontiersin.org
Cancer is commonly thought to be the product of irregular cell division. According to the
World Health Organization (WHO), cancer is the major cause of death globally. Nature offers …

Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Natural products as anticancer agents: Current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Plant natural products: from traditional compounds to new emerging drugs in cancer therapy

L Ouyang, Y Luo, M Tian, SY Zhang, R Lu… - Cell …, 2014 - Wiley Online Library
Natural products are chemical compounds or substances produced naturally by living
organisms. With the development of modern technology, more and more plant extracts have …

[HTML][HTML] Perspectives on natural compounds in chemoprevention and treatment of cancer: an update with new promising compounds

A Haque, D Brazeau, AR Amin - European Journal of Cancer, 2021 - Elsevier
Cancer is the second deadliest disease worldwide. Although recent advances applying
precision treatments with targeted (molecular and immune) agents are promising, the …

Natural health products (NHP's) and natural compounds as therapeutic agents for the treatment of cancer; mechanisms of anti-cancer activity of natural compounds …

B Scaria, S Sood, C Raad, J Khanafer… - International Journal of …, 2020 - mdpi.com
Most cancer therapeutics, such as tubulin-targeting chemotherapy drugs, cause cytotoxic,
non-selective effects. These harmful side-effects drastically reduce the cancer patient's …