Major depressive disorder (MDD) is the most common mental illness and the leading cause
of disability worldwide. Electroconvulsive therapy (ECT) is the most effective treatment for …

Objective: Ketamine has repeatedly shown to have rapid and robust antidepressant effects
in patients with treatment resistant depression (TRD). An important question is whether …

Background Electroconvulsive therapy (ECT) and subanesthetic intravenous ketamine are
both currently used for treatment-resistant major depression, but the comparative …

Major depressive disorder (MDD) is a highly incapacitating condition that has a significant
impact on a large number of individuals worldwide, representing the greatest burden of …

This Viewpoint examines key issues stemming from severalrecentreportsofelectroconvulsivether…
(ECT) vs ketamine infusion for improving depressive symptoms in treatment-resistant …

Abstract Background and Aims Ketamine and esketamine have garnered interest in both
psychiatric research and clinical practice for treatment-resistant depression (TRD). In this …

Importance The relative efficacy of ketamine and electroconvulsive therapy (ECT) in adults
with major depressive episode (MDE) needs clarification. Objective To compare depression …

Importance Whether ketamine is as effective as electroconvulsive therapy (ECT) among
patients with major depressive episode remains unknown. Objective To systematically …

Background Electroconvulsive therapy (ECT) remains one of the most effective tools in the
psychiatric treatment armamentarium, particularly for refractory depression. Yet, there …

Background There is an urgent need to develop additional treatment strategies for patients
with treatment-resistant depression (TRD). The rapid but short-lived antidepressant effects of …