Comparative functional analysis of the urinary tract microbiome for individuals with or without calcium oxalate calculi

N Kachroo, M Monga, AW Miller - Urolithiasis, 2022 - Springer
Individuals with urinary stone disease (USD) exhibit dysbiosis in the urinary tract and the
loss of Lactobacillus that promote urinary tract health. However, the microbial metabolic …

The urinary microbiota composition and functionality of calcium oxalate stone formers

J Xie, X Zhang, J Guo, Q Yuan, K Xiao… - Frontiers in Cellular and …, 2024 - frontiersin.org
Background Accumulated evidences indicate that dysbiosis of the urinary microbiota is
associated with kidney stone formation. In the present study, we aimed to investigate the …

[HTML][HTML] Update on the Effect of the Urinary Microbiome on Urolithiasis

HD Jung, S Cho, JY Lee - Diagnostics, 2023 - mdpi.com
Microbiota are ecological communities of commensal, symbiotic, and pathogenic
microorganisms. The microbiome could be involved in kidney stone formation through …

[HTML][HTML] Defining dysbiosis in patients with urolithiasis

A Zampini, AH Nguyen, E Rose, M Monga, AW Miller - Scientific reports, 2019 - nature.com
The prevalence of urinary stone disease (USD) is rapidly rising. However, the factors driving
this increase are unknown. Recent microbiome studies suggest that dysbiosis may in part …

[HTML][HTML] The genetics of urinary microbiome, an exploration of the trigger in calcium oxalate stone

Y Yang, L Miao, Y Lu, S Wang - Frontiers in Genetics, 2023 - frontiersin.org
Background: Kidney stone disease is a global disease; however, it has not been totally
understood. Calcium oxalate (CaOx) stone is the dominant type of kidney stone, and the …

Understanding the gut–kidney axis in nephrolithiasis: an analysis of the gut microbiota composition and functionality of stone formers

A Ticinesi, C Milani, A Guerra, F Allegri, F Lauretani… - Gut, 2018 - gut.bmj.com
Objectives The involvement of the gut microbiota in the pathogenesis of calcium
nephrolithiasis has been hypothesised since the discovery of the oxalate-degrading activity …

[HTML][HTML] Inhibition of urinary stone disease by a multi-species bacterial network ensures healthy oxalate homeostasis

AW Miller, D Choy, KL Penniston, D Lange - Kidney international, 2019 - Elsevier
The incidence of urinary stone disease is rapidly increasing, with oxalate being a primary
constituent of approximately 80% of all kidney stones. Despite the high dietary exposure to …

Calcium oxalate urolithiasis: a case of missing microbes?

CA Batagello, M Monga, AW Miller - Journal of endourology, 2018 - liebertpub.com
Introduction: Urinary stone disease (USD) has known associations with the gut microbiota.
Approximately 80% of kidney stones contain oxalate as a primary constituent and diverse …

Mechanisms of the intestinal and urinary microbiome in kidney stone disease

AW Miller, KL Penniston, K Fitzpatrick… - Nature Reviews …, 2022 - nature.com
Kidney stone disease affects~ 10% of the global population and the incidence continues to
rise owing to the associated global increase in the incidence of medical conditions …

Perturbations of the gut microbiome and metabolome in children with calcium oxalate kidney stone disease

MR Denburg, K Koepsell, JJ Lee, J Gerber… - Journal of the …, 2020 - journals.lww.com
Background The relationship between the composition and function of gut microbial
communities and early-onset calcium oxalate kidney stone disease is unknown. Methods …