Background: Prompt myocardial revascularisation with percutaneous coronary intervention
(PCI) reduces infarct size and improves outcomes in patients with acute ST segment …

Background Prompt myocardial revascularization with percutaneous coronary intervention
(PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation …

Despite urgent myocardial reperfusion with percutaneous coronary intervention (PCI),
morbidity and mortality remain substantial in patients presenting with acute myocardial …

Introduction Interleukin-6 (IL-6) may be involved in ischaemia-reperfusion injury and
myocardial remodelling after myocardial infarction (MI). We have recently shown that IL-6 …

Introduction: Increased levels of the inflammatory cytokine interleukin 6 (IL-6) after
percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) are …

A new randomized clinical trial shows that tocilizumab, a monoclonal antibody that inhibits IL-
6 signalling by binding to the IL-6 receptor, increases myocardial salvage in patients with …

Background We recently showed that interleukin (IL)-6 inhibition by tocilizumab improves
myocardial salvage in ST-elevation myocardial infarction (STEMI). However, the …

Background Inflammation has emerged as a new treatment target in patients with coronary
artery disease, and inflammation seems to play an important role in the ischemia/reperfusion …

Two pilot studies of interleukin-1 (IL-1) blockade in ST-segment elevation myocardial
infarction (STEMI) showed blunted acute inflammatory response and overall favorable …

Abstract Background: Interleukin‐1 receptor antagonist (IL‐1 Ra) levels are elevated early in
patients with acute myocardial infarction (MI) and often precede release of markers of …