Quantitative assessment of changes in cellular morphology at photodynamic treatment in vitro by means of digital holographic microscopy

AV Belashov, AA Zhikhoreva, TN Belyaeva… - Biomedical optics …, 2019 - opg.optica.org
Temporal dependence of changes in the morphological characteristics of cells of two
cultured lines of cancer origin, HeLa and A549, induced by photodynamic treatment with …

Digital holographic microscopy in label-free analysis of cultured cells' response to photodynamic treatment

AV Belashov, AA Zhikhoreva, TN Belyaeva… - Optics letters, 2016 - opg.optica.org
A methodology providing noninvasive monitoring and evaluation of the effect of
photodynamic treatment on live cells in vitro is presented. Variations in morphological …

[HTML][HTML] Significant difference in response of malignant tumor cells of individual patients to photodynamic treatment as revealed by digital holographic microscopy

AA Zhikhoreva, AV Belashov, AB Danilova… - … of Photochemistry and …, 2021 - Elsevier
The investigation of in-vitro response of cell cultures derived from tumor material of
individual patients with similar tumor localizations to photodynamic treatment is presented …

Changes in optical properties of electroporated cells as revealed by digital holographic microscopy

VL Calin, M Mihailescu, N Mihale, AV Baluta… - Biomedical Optics …, 2017 - opg.optica.org
Changes in optical and shape-related characteristics of B16F10 cells after electroporation
were investigated using digital holographic microscopy (DHM). Bipolar rectangular pulses …

Multimodal label-free in vitro toxicity testing with digital holographic microscopy

CE Rommel, C Dierker, A Vollmer… - … Solutions for Better …, 2014 - spiedigitallibrary.org
Common in vitro toxicity tests of drugs, chemicals or nanomaterials involves the
measurement of cellular endpoints like stress response, cell viability, proliferation or cell …

Investigating fibroblast cells under “safe” and “injurious” blue‐light exposure by holographic microscopy

A Calabuig, M Mugnano, L Miccio, S Grilli… - Journal of …, 2017 - Wiley Online Library
The exposure to visible light has been shown to exert various biological effects, such as
erythema and retinal degeneration. However, the phototoxicity mechanisms in living cells …

Noninvasive time-dependent cytometry monitoring<? xpp qa?> by digital holography

M Kemmler, M Fratz, D Giel, N Saum… - … of biomedical optics, 2007 - spiedigitallibrary.org
Using a digital holographic microscope setup, it is possible to measure dynamic volume
changes in living cells. The cells were investigated time-dependently in transmission mode …

Comparative analysis of Radachlorin accumulation, localization, and photobleaching in three cell lines by means of holographic and fluorescence microscopy

AA Zhikhoreva, AV Belashov, TN Belyaeva… - Photodiagnosis and …, 2022 - Elsevier
In this paper we compare the response of cells of established lines of different origin: HeLa,
A549 and 3T3 to photodynamic treatment with Radachlorin photosensitizer. The analysis …

Digital holographic microscopy: innovative and non-destructive analysis of living cells

Z El-Schich, A Mölder, M Sebesta, L Gisselsson, K Alm… - 2010 - diva-portal.org
Abstracts of proposals for the book titled: Microscopy: Science, Technology, Applications
and Education Digital holography is a novel technique that has been developed recently to …

In vitro monitoring of photoinduced necrosis in HeLa cells using digital holographic microscopy and machine learning

AV Belashov, AA Zhikhoreva, TN Belyaeva… - JOSA A, 2020 - opg.optica.org
Digital holographic microscopy supplemented with the developed cell segmentation and
machine learning and classification algorithms is implemented for quantitative description of …