Cell morphology is the research foundation in many applications related to the estimation of
cell status, drug response, and toxicity screening. In biomedical field, the quantitative phase …

Optical tweezers are a versatile technique to manipulate living biological specimen in a
contact-less way. The interaction with living cells can be performed, for example, through …

For the analysis of the impact of pharmaceuticals or pathogens on different cellular
phenotypes under identical measurement conditions and to analyze interactions between …

Digital holographic microscopy (DHM) allows optical-path-difference (OPD) measurements
with nanometric accuracy. OPD induced by transparent cells depends on both the refractive …

The understanding of biological reactions and evaluation of the significance for living cells
strongly depends on the ability to visualize and quantify these processes. Digital …

For a precise manipulation of particles and cells with laser light as well as for the
understanding and the control of the underlying processes it is important to visualize and …

Observation of three-dimensional (3D) morphology changes of a single mammalian cell is
very useful to understand cell response for various stimuli. Conventional techniques to …

Featured Application Quantitative phase imaging (QPI) and holographic microscopy (HM)
are suitable methods for long-term and label-free imaging of cells and for the complex …

Phase-derived parameters and time autocorrelation functions were used to analyze the
behavior of murine B16 cells exposed to different amplitudes of electroporation pulses. Cells …

Cancer cell motility and invasion are critical targets for anticancer therapeutics. Whereas in
vitro models could be designed for rapid screening with a view to investigate these targets …