Pericytes constrict blood vessels after myocardial ischemia
MA Costa, AE Paiva, JP Andreotti, MV Cardoso… - Journal of molecular and …, 2018 - Elsevier
No-reflow phenomenon is defined as the reduced blood flow after myocardial ischemia. If
prolonged it leads to profound damages in the myocardium. The lack of a detailed …
prolonged it leads to profound damages in the myocardium. The lack of a detailed …
A role for pericytes in coronary no-reflow
FM O'farrell, D Attwell - Nature reviews cardiology, 2014 - nature.com
Despite efforts to restore tissue perfusion after myocardial infarction, coronary no-reflow—a
failure to achieve adequate reperfusion of the cardiac microcirculation—is a common …
failure to achieve adequate reperfusion of the cardiac microcirculation—is a common …
Mechanisms of the “no-reflow” phenomenon after acute myocardial infarction: Potential role of pericytes
Pericytes contract during myocardial ischemia resulting in capillary constriction and no
reflow. Reversing pericyte contraction pharmacologically reduces no reflow and infarct size …
reflow. Reversing pericyte contraction pharmacologically reduces no reflow and infarct size …
Mechanism and potential treatment of the “no reflow” phenomenon after acute myocardial infarction: role of pericytes and GPR39
C Methner, Z Cao, A Mishra… - American Journal of …, 2021 - journals.physiology.org
The “no reflow” phenomenon, where the coronary artery is patent after treatment of acute
myocardial infarction (AMI) but tissue perfusion is not restored, is associated with worse …
myocardial infarction (AMI) but tissue perfusion is not restored, is associated with worse …
No-reflow phenomenon: maintaining vascular integrity
RA Kloner - Journal of cardiovascular pharmacology and …, 2011 - journals.sagepub.com
The no-reflow phenomenon relates to the inability to reperfuse regions of the myocardium
after ischemia, despite removal of the large epicardial coronary artery occlusion. The …
after ischemia, despite removal of the large epicardial coronary artery occlusion. The …
Capillary pericytes mediate coronary no-reflow after myocardial ischaemia
After cardiac ischaemia, a prolonged decrease of coronary microvascular perfusion often
occurs even after flow is restored in an upstream artery. This' no-reflow'phenomenon …
occurs even after flow is restored in an upstream artery. This' no-reflow'phenomenon …
Paeonol protects rat heart by improving regional blood perfusion during no-reflow
L Ma, CC Chuang, W Weng, L Zhao, Y Zheng… - Frontiers in …, 2016 - frontiersin.org
No-reflow phenomenon, defined as inadequate perfusion of myocardium without evident
artery obstruction, occurs at a high incidence after coronary revascularization. The …
artery obstruction, occurs at a high incidence after coronary revascularization. The …
No-reflow phenomenon. A new target for therapy of acute myocardial infarction independent of myocardial infarct size
The no-reflow phenomenon is a failure to reperfuse portions of previously ischemic tissue
when patency of the large arteries perfusing an organ has been reestablished. This …
when patency of the large arteries perfusing an organ has been reestablished. This …
Losartan protects against myocardial ischemia and reperfusion injury via vascular integrity preservation
Y Li, Y Yao, J Li, Q Chen, L Zhang… - The FASEB …, 2019 - Wiley Online Library
Vascular hyperpermeability caused by distorted endothelial cell‐cell junctions is associated
with the no‐reflow phenomenon after opening of the occluded vessels in patients with …
with the no‐reflow phenomenon after opening of the occluded vessels in patients with …
Different effects of adenosine and calcium channel blockade on myocardial no-reflow after acute myocardial infarction and reperfusion
JL Zhao, YJ Yang, CJ Cui, SJ You, YJ Wu… - … drugs and therapy, 2006 - Springer
Background Adenosine and calcium channel blockers have been used in the treatment of
angiographic no-reflow directly after angioplasty for acute myocardial infarction (AMI) …
angiographic no-reflow directly after angioplasty for acute myocardial infarction (AMI) …