Background: There has been increasing interest in transnasal pulmonary aerosol
administration, but the dose-response relationship has not been reported. Objectives: To …

(1) Background: Aerosol delivery via high-flow nasal cannula (HFNC) has attracted
increasing clinical interest. In vitro studies report that the ratio of HFNC gas flow to patient …

Trans-nasal aerosol deposition during distressed breathing is higher than quiet breathing,
and decreases as administered gas flow increases. We hypothesize that inhaled dose is …

Background: Nasal high flow (NHF) alters breathing patterns, stabilizes fraction of inspired
oxygen (FiO2) during respiratory distress, helps to keep up hemostasis in the airways, and …

Background: Obstructive patients may benefit from nasal high-flow (NHF) therapy, but the
use of pressurized metered-dose inhalers (pMDIs) has not been evaluated in this situation …

Background: Trans-nasal pulmonary aerosol delivery using high flow nasal cannula (HFNC)
devices is described with the administration of high gas flows exceeding patient inspiratory …

Background There is an absence of controlled clinical data showing bronchodilation
effectiveness after nebulization via nasal high-flow therapy circuits. Results Twenty-five …

BACKGROUND: Aerosol delivery via high-flow nasal cannula (HFNC) has been
increasingly used in recent years. However, the effects of different HFNC devices, nebulizer …

BACKGROUND: The metered-dose inhaler is currently one of the most prescribed methods
of delivering drugs to the lungs. In the United States, most currently marketed metered-dose …

High-flow nasal cannula (HFNC) therapy is an oxygen delivery method particularly used in
patients affected by hypoxemic respiratory failure. In comparison with the conventional “low …