Diabetes from pancreatic β cell death and insulin resistance is a serious metabolic disease
in the world. Although the overproduction of mitochondrial reactive oxygen species (ROS) …

Type 1 diabetes mellitus (T1DM) is caused by pancreatic β-cell dysfunction and apoptosis,
with consequent severe insulin deficiency. Thus, β-cell protection may be a primary target in …

Insulin-producing cells express limited activities of anti-oxidative enzymes. Therefore,
reactive oxygen species (ROS) produced in these cells play a crucial role in cytotoxic effects …

Diabetes mellitus (DM) is a metabolic syndrome, caused by insufficient insulin secretion or
insulin resistance (IR). DM enhances oxidative stress and induces mitochondrial function in …

Background Coix seed oil (CSO) has a wide range of anticancer effects. However, the
mechanism of action against pancreatic cancer (PC) and regulation of mitochondria in vitro …

Electrolyzed reduced water, which is capable of scavenging reactive oxygen species, is
attracting recent attention because it has shown improved efficacy against several types of …

Mitochondrial injury characterized by intracellular reactive oxygen species (ROS)
accumulation plays a critical role in hyperglycemia-induced myocardium dysfunction …

The purpose of this study is to explore the possible link between oxidative stress and
endoplasmic reticulum (ER) stress in palmitate (PA) induced apoptosis of INS-1 cells, and to …

Type 2 diabetes mellitus is characterized by insulin resistance and pancreatic beta (β)-cell
dysfunction. Accumulating evidence suggests that mitochondrial dysfunction may cause …

Lipotoxicity plays a vital role in development and progression of type 2 diabetes. Prolonged
elevation of free fatty acids especially the palmitate leads to pancreatic β-cell dysfunction …