Preeclampsia is a common pregnancy-related hypertensive disorder. Often presenting as
preexisting or new-onset hypertension complicated by proteinuria and/or end-organ …

Preeclampsia is a multisystemic disorder of pregnancy characterized by hypertension,
proteinuria, and maternal endothelial dysfunction. It is a major cause of maternal and …

Preeclampsia, a major cause of maternal and perinatal mortality and morbidity, is thought to
be attributed, in part, to impaired trophoblast invasion. Peroxisome proliferator-activated …

Peroxisome proliferator-activated receptor γ (PPARγ) is essential for placental development,
whose SNPs have shown increased susceptibility to pregnancy-related diseases, such as …

During pregnancy crucial anatomic, physiologic, and metabolic changes challenge the
mother and the fetus. The placenta is a remarkable organ that allows the mother and the …

BACKGROUND: Common complications of pregnancy arise in part from dysfunctional
placental development, and include gestational diabetes mellitus (GDM), intrauterine growth …

Peroxisome proliferator activated receptors (PPARs) are ligand‐activated transcription
factors expressed in trophoblasts, which regulate both cell differentiation and proliferation. In …

Objectives Human and animal studies have demonstrated that peroxisome proliferator-
activated receptors (PPARs) are important in placental development and play key roles in …

Preeclampsia (PE) is one of the most common causes of maternal-fetal morbidity and
mortality world-wide. While the underlying causes of PE remain elusive, aberrant trophoblast …

We previously described activators of peroxisome proliferator-activated receptor γ (PPARγ)
in the serum of pregnant women. We have also characterized this activating component by …