[HTML][HTML] Vasodilatory effects of cannabidiol in human pulmonary and rat small mesenteric arteries: Modification by hypertension and the potential pharmacological …
M Baranowska-Kuczko, H Kozlowska… - Journal of …, 2020 - journals.lww.com
Objective: Cannabidiol (CBD) has been suggested as a potential antihypertensive drug. The
aim of our study was to investigate its vasodilatory effect in isolated human pulmonary …
aim of our study was to investigate its vasodilatory effect in isolated human pulmonary …
[HTML][HTML] Vasoprotective endothelial effects of chronic cannabidiol treatment and its influence on the endocannabinoid system in rats with primary and secondary …
M Baranowska-Kuczko, H Kozłowska, M Kloza… - Pharmaceuticals, 2021 - mdpi.com
Our study aimed to examine the endothelium (vascular)-protecting effects of chronic
cannabidiol (CBD) administration (10 mg/kg once daily for 2 weeks) in aortas and small …
cannabidiol (CBD) administration (10 mg/kg once daily for 2 weeks) in aortas and small …
Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation
Aims The protective effects of cannabidiol (CBD) have been widely shown in preclinical
models and have translated into medicines for the treatment of multiple sclerosis and …
models and have translated into medicines for the treatment of multiple sclerosis and …
Identification of the vasodilatory endothelial cannabinoid receptor in the human pulmonary artery
H Kozlowska, M Baranowska, E Schlicker… - Journal of …, 2007 - journals.lww.com
Background The endocannabinoid anandamide is implicated in the pathogenesis of
hypotension in haemorrhagic, endotoxic, and cardiogenic shock. It has been demonstrated …
hypotension in haemorrhagic, endotoxic, and cardiogenic shock. It has been demonstrated …
[HTML][HTML] In Vivo Cannabidiol Treatment Improves Endothelium-Dependent Vasorelaxation in Mesenteric Arteries of Zucker Diabetic Fatty Rats
AJ Wheal, K Jadoon, MD Randall… - Frontiers in …, 2017 - frontiersin.org
Background and purpose: We have shown that in vitro treatment with cannabidiol (CBD, 2 h)
enhances endothelial function in arteries from Zucker diabetic fatty (ZDF) rats, partly due to a …
enhances endothelial function in arteries from Zucker diabetic fatty (ZDF) rats, partly due to a …
[HTML][HTML] Chronic cannabidiol administration fails to diminish blood pressure in rats with primary and secondary hypertension despite its effects on cardiac and plasma …
P Remiszewski, I Jarocka-Karpowicz… - International Journal of …, 2020 - mdpi.com
We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate
(HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats …
(HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats …
[HTML][HTML] Cannabidiol ameliorates monocrotaline-induced pulmonary hypertension in rats
O Sadowska, M Baranowska-Kuczko… - International Journal of …, 2020 - mdpi.com
Cannabidiol (CBD) is known for its vasorelaxant (including in the human pulmonary artery),
anti-proliferative and anti-inflammatory properties. The aim of our study was to examine the …
anti-proliferative and anti-inflammatory properties. The aim of our study was to examine the …
Cannabidiol improves vasorelaxation in Zucker diabetic fatty rats through cyclooxygenase activation
AJ Wheal, M Cipriano, CJ Fowler, MD Randall… - … of Pharmacology and …, 2014 - ASPET
Cannabidiol (CBD) decreases insulitis, inflammation, neuropathic pain, and myocardial
dysfunction in preclinical models of diabetes. We recently showed that CBD also improves …
dysfunction in preclinical models of diabetes. We recently showed that CBD also improves …
Vasodilator actions of abnormal‐cannabidiol in rat isolated small mesenteric artery
WS Vanessa Ho, CR Hiley - British journal of pharmacology, 2003 - Wiley Online Library
The nonpsychoactive cannabinoid abnormal‐cannabidiol (trans‐4‐[3‐methyl‐6‐(1‐
methylethenyl)‐2‐cyclohexen‐1‐yl]‐5‐pentyl‐1, 3‐benzenediol)(abn‐cbd) produced …
methylethenyl)‐2‐cyclohexen‐1‐yl]‐5‐pentyl‐1, 3‐benzenediol)(abn‐cbd) produced …
[HTML][HTML] CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial
M Kumric, G Dujic, J Vrdoljak, K Svagusa… - Biomedicine & …, 2023 - Elsevier
Data concerning the effects of cannabidiol (CBD) on blood pressure (BP) is controversial.
HYPER-H21–4 was a randomized, placebo-controlled, crossover trial which sought to …
HYPER-H21–4 was a randomized, placebo-controlled, crossover trial which sought to …