Mangiferin is a xanthone glucoside extracted from multiple plants, which has been shown to
inhibit bone resorption and alleviate osteoporosis. However, the effect of purified Mangiferin …

Mangiferin is a polyphenolic compound present in Salacia reticulata. It has been reported to
reduce bone destruction and inhibit osteoclastic differentiation. This study aimed to …

Background Ferroptosis is a crucial contributor to impaired osteoblast function in
osteoporosis. Mangiferin, a xanthonoid glucoside isolated from mangoes, exhibits anti …

Osteolytic bone diseases such as osteoporosis have a common pathological feature in
which osteoclastic bone resorption outstrips bone synthesis. Osteoclast formation and …

Oxidative stress has currently been proposed as a risk factor associated with the
development and proression of osteoporosis. In this study, we identify the effect of …

Osteoporosis is caused by disturbance in the dynamic balance of bone remodelling, a
physiological process, vital for maintenance of healthy bone tissue in adult humans. In this …

Chemerin, a secreted protein mainly produced by adipocytes and hepatocytes, plays a
variety of roles in endocrine or paracrine signaling. As reported in human epidemiology …

Geraniin is an ellagitannin isolated from Phyllanthus amarus and has a wide range of
bioactivities. Our previous study demonstrated that geraniin could alleviate osteoporosis by …

Background Osteoporosis (OP) is a metabolic bone disease due to the imbalance of
osteogenesis and bone resorption, in which, bone marrow mesenchymal stem cells …

Mangiferin has demonstrated in vitro inhibitory influence on RANKL (Receptor Activator of
Nuclear Factor Kappa B Ligand) mediated osteoclasts activity. In this study we evaluated the …