This review proposes that the development of the atherosclerotic plaque is critically
dependent on its inflammatory components forming a self-perpetuating and propagating …

Although the pathophysiological mechanisms underlying atherosclerosis are not completely
understood, it is widely recognized that both inflammation and oxidative stress play …

Sound data support the concept that in atherosclerosis, inflammation and dyslipidemia
intersect each other and that irrespective of the initiator, both participate from the early …

Atherosclerosis is the anatomo-pathological substrate of most cardio, cerebro and vascular
diseases such as acute and chronic coronary syndromes, stroke and peripheral artery …

The objective of this communication is to develop a computer-based framework for the
overall coupled phenomena leading to growth and rupture of atherosclerotic plaques. The …

Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

The adventitia and the outer layers of media of an atherosclerosis-prone arterial wall are
vascularized by vasa vasorum. Upon growth of an atherosclerotic lesion in the intima …

It is now widely accepted that the development of atherosclerotic lesions involves a chronic
inflammatory response that includes both innate and adaptive immune mechanisms …

Atherosclerotic plaque formation involves 5 steps: 1. low density lipoprotein (LDL)
accumulation in the intima; 2. oxidation of LDL; 3. recruitment of monocytes-macrophages; 4 …