Urogenital Chlamydia trachomatis infection is the most common sexually transmitted
bacterial infection throughout the world. While progress has been made to better understand …

Research on the obligate intracellular bacterium Chlamydia trachomatis demands culture in
cell-lines, but the adaptive process behind the in vivo to in vitro transition is not understood …

Background Despite small genomic differences, Chlamydia trachomatis biovars exhibit
diverse disease manifestations and different growth rates in vivo and in cell culture models …

It is assumed that bacterial strains maintained in the laboratory for long time shape their
genome in a different fashion from the nature-circulating strains. Here, we analyzed the …

Chlamydia infection targets the mucosal epithelium, where squamous and columnar
epithelia can be found. Research on Chlamydia-epithelia interaction has predominantly …

Chlamydia trachomatis is a human pathogen of global importance. An obstacle to studying
the pathophysiology of human chlamydial disease is the lack of a suitable murine model of …

The association of infectious burden of Chlamydia trachomatis with patient characteristics
and clinical disease may have implications for understanding disease pathogenesis. We …

Objectives Antimicrobial susceptibility data for Chlamydia trachomatis are lacking.
Methodologies for susceptibility testing in C. trachomatis are not well-defined, standardized …

Background. The biology of recurrent or long-term infections of humans by Chlamydia
trachomatis is poorly understood. Because repeated or persistent infections are correlated …

Chlamydia pneumoniae strains have recently been demonstrated to have substantially
different capacities to enter and recover from IFN-γ-induced persistence, depending on …