Breast cancer is categorized at the molecular level according to the status of certain
hormone and growth factor receptors, and this classification forms the basis of current …

The discovery of the molecular processes involved in cancer development has led to the
design of an array of targeted agents. These agents, directed to specific proteins in the …

Over the past several years significant advances have been made in our understanding of a
growing number of critical pathways involved in breast cancer. These advances have led to …

Although the introduction of novel therapies and drug combinations has improved the
prognosis of metastatic breast cancer, the disease remains incurable. Increased knowledge …

In the United States, breast cancer is among the most frequently diagnosed cancers in
women. Breast cancer is classified into four major subtypes: human epidermal growth factor …

Breast cancer is a multistep, multifactorial, and heterogeneous disease. Significant
transformations have occurred in the systemic management of breast cancer in the past …

In recent years, there has been a significant improvement in the understanding of molecular
events and critical pathways involved in breast cancer. This has led to the identification of …

Breast cancer is the most frequent tumor of women. The development of effective adjuvant
therapy based on postoperative administration of short-term chemotherapy (4-6 months) or …

Human breast cancer treatment regimens have evolved greatly due to the significant
advances in understanding the molecular mechanisms and pathways of the common …

Introduction Breast cancer is the most common female cancer and the second most common
cause of female cancer-related deaths in the United States. World-wide, more than one …