Abstract Background Mitochondrial DNA (mtDNA) copy number in oocytes correlates with
oocyte quality and fertilisation outcome. The introduction of additional copies of mtDNA …

Mitochondrial DNA (mtDNA) deficiency correlates with poor oocyte quality and fertilisation
failure. However, the supplementation of mtDNA deficient oocytes with extra copies of …

Mitochondrial DNA (mtDNA) deficient metaphase II porcine oocytes are less likely to fertilize
and more likely to arrest during preimplantation development. However, they can be …

STUDY QUESTION What are the molecular differences between mitochondrial DNA
(mtDNA)-deficient and mtDNA-normal oocytes and how does mitochondrial …

Abstract Comparison of mitochondrial DNA (mtDNA) methylation patterns in oocytes,
blastocysts and ovarian granulosa cells indicates hitherto unsuspected dynamics. Oocytes …

Global mitochondrial DNA (mtDNA) methylation has been recently described in bovine and
showed particular signatures in both gametes and embryos. Here, we investigated the …

This study characterized variations in the methylation profile of mitochondrial DNA (mtDNA)
during initial bovine embryo development and correlated the presence of methylation with …

Mitochondria are responsible for the production of ATP, which drives cellular metabolic and
biosynthetic processes. This is the first study to quantify the mtDNA copy number across all …

Introducing extra mitochondrial DNA (mtDNA) into oocytes at fertilization can rescue poor
quality oocytes. However, supplementation alters DNA methylation and gene expression …

The mitochondrial genome resides in the mitochondria present in nearly all cell types. The
porcine (Sus scrofa) mitochondrial genome is circa 16.7 kb in size and exists in the …