Cryptococcus neoformans is a ubiquitous environmental fungus and opportunistic human
pathogen, primarily impacting immunocompromised hosts such as those living with …

In response to the host environment, the human pathogen Cryptococcus neoformans must
rapidly reprogram its translatome from one which promotes growth to one which is …

Cryptococcus neoformans is an environmental fungus that can cause severe disease in
humans. C. neoformans encounters a multitude of stresses within the human host to which it …

Cryptococcus neoformans is a ubiquitous environmental fungus capable of establishing an
infection in a human host. Rapid changes in environments and exposure to the host immune …

Cryptococcus neoformans is one of the few environmental fungi that can survive within a
mammalian host and cause disease. Although many of the factors responsible for …

Fungi are ubiquitous in the environment and humans constantly encounter them in the soil,
air, water, and food. The vast majority of these interactions are inconsequential. However, in …

A common feature shared by systemic fungal pathogens of environmental origin, such as
Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In …

Adaptation to host temperature is a prerequisite for any pathogen capable of causing deep
infection in humans. Our previous studies demonstrated that a Cryptococcus neoformans …

Cryptococcus neoformans is one of the few environmental fungi that can adapt to a
mammalian host and cause disease. As free a living organism, C. neoformans is challenged …

The fungal pathogen Cryptococcus neoformans relies on post-transcriptional mechanisms of
gene regulation to adapt to stressors it encounters in the human host, such as oxidative …