Metabolically quiescent pathogens can persist in a viable non-replicating state for months or
even years. For certain infectious diseases, such as tuberculosis, cryptococcosis …

By controlling gene expression at the level of mRNA translation, organisms temporally and
spatially respond swiftly to an ever-changing array of environmental conditions. This …

Cold-shocked bacteria transiently shut down protein translation, but the mechanisms
whereby they adaptively restore translation were incompletely understood. Zhang et …

Morphotype switch is a cellular response to external and internal cues. The Cryptococcus
neoformans species complex can undergo morphological transitions between the yeast and …

Flexible adaptation to environmental stress is vital for bacteria. An energy-efficient post-
transcriptional stress response mechanism in Escherichia coli is governed by the toxin …

Autophagy is mainly a catabolic process, which is used to cope with nutrient deficiency and
various stress conditions. Human environment often imposes various stresses on …

Bacteria of class Mollicutes (mycoplasmas) feature significant genome reduction which
makes them good model organisms for systems biology studies. Previously we …

Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific
protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus …

Heat shock response is a classical stress-induced regulatory system in bacteria,
characterized by extensive transcriptional reprogramming. To compare the impact of heat …