High activation of the angiotensin-converting enzyme (ACE)/(angiotensin-II type 1 receptor)
AT1r axis is closely linked to pro-inflammatory effects and liver damage. The aim of this …

Angiotensin (Ang)-(1–7) has been described as an important tool on treating and preventing
metabolic disorders. In this study, we aimed to evaluate the effect of an oral formulation of …

Nonalcoholic steatohepatitis (NASH), a potential consequence of NAFLD, may lead to end
stage liver disease including cirrhosis and hepatocellular carcinoma. Despite its severity …

Nonalcoholic steatohepatitis (NASH) is a progressive liver disease characterized by
steatosis and inflammation, which results in fibrosis. In particular, advanced fibrosis due to …

This study was designed to investigate the antioxidative, antiinflammatory and metabolism‐
regulating effects of gastrodin (GSTD) in the treatment of nonalcoholic fatty liver disease …

Aim. Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, and if untreated, it may propagate into end‐stage liver disease. The classical arm …

Gypenosides (GP), extracted from the traditional Chinese herb Gynostemma pentaphyllum
(Thunb.) Makino, have been used to treat metabolic disorders, including lipid metabolism …

Background The contents of lipopolysaccharide (LPS) and Toll-like receptor 4 (TLR4) are
significantly increased during the progression of nonalcoholic fatty liver disease (NAFLD) …

Introduction: Our previous study demonstrated that docosahexaenoic acid (DHA), an
endogenous G protein-coupled receptor 120 (GPR120)/free fatty acid receptor (FFAR) 4 …

Although peroxisome proliferator receptor (PPAR)-α and PPAR-γ agonist have been
developed as chemical tools to uncover biological roles for the PPARs such as lipid and …