B cells and T cells are two major players in the pathogenesis of multiple sclerosis (MS) and
cooperate at various check points. B cells, besides serving as a source for antibody …

Multiple sclerosis afflicts more than 1 million individuals worldwide and is widely considered
to be an autoimmune disease. Traditionally, CD4+ T helper cells have almost exclusively …

Multiple sclerosis (MS) is the most common human demyelinating disease of the central
nervous system. It is universally accepted that the immune system plays a major role in the …

Multiple sclerosis (MS) is the leading cause of chronic neurological disability in young
adults. The clinical disease course of MS varies greatly between individuals, with some …

Multiple sclerosis (MS), a neuroinflammatory disease that affects millions worldwide, is
widely thought to be autoimmune in etiology. Historically, research into MS pathogenesis …

Epstein‐Barr virus (EBV) has long been suggested as a pathogen in multiple sclerosis (MS).
Here, we used high‐throughput sequencing to determine the diversity …

There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis
(MS). The success of B‐cell targeting therapies in MS highlighted the role of B cells …

Background: Collectively, research on the role of B-cells in the pathogenesis of multiple
sclerosis (MS) illustrates how translational medicine has given rise to promising therapeutic …

It was hypothesized that the EBV-specific CD8+ T cell response may be dysregulated in
multiple sclerosis (MS) patients, possibly leading to a suboptimal control of this virus. To …

Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …