Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis
(EAE) have long been regarded as primarily T helper cell type 1-mediated diseases …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) of putative autoimmune origin. Recent evidence indicates that MS …

Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
pathologically characterized by lesions of infiltrating macrophages and T cells. Multiple lines …

Neurocognitive impairment (NCI) is one of the most relevant clinical manifestations of
multiple sclerosis (MS). The profile of NCI and the structural and functional changes in the …

In the MOG 35–55 induced EAE model, autoreactive T h17 cells that accumulate in the
central nervous system acquire T h1 characteristics via a T‐bet dependent mechanism. It …

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …

The antigen-specific activation of pathogenic T cells is considered essential in the initiation
and maintenance of multiple sclerosis (MS). The site of activation, the differential …

Although experimental autoimmune encephalomyelitis (EAE) is limited in its potency to
reproduce the entirety of clinical and histopathologic features of multiple sclerosis (MS), this …

Pathogenic mechanisms of T cells in several central nervous system (CNS) disorders are
well-established. However, more recent studies have uncovered compelling beneficial roles …