Telomere repeats at the ends of human chromosomes protect chromosomes from
degradation, and telomerase has a prominent role in telomere maintenance. Telomerase …

Telomere repeats protect linear chromosomes from degradation, and telomerase has a
prominent role in their maintenance. Telomerase has telomere-independent effects on cell …

Telomeres are guanine-rich 5'-TTAGGG-3'repeats found at the ends of human
chromosomes that protect chromosomes from degradation and also provide stabilization …

Telomere maintenance is a hallmark of human cancer. In the majority of human cancer,
telomere maintenance is achieved by reactivation of telomerase. TERT–a reverse …

Recent evidence points to extra-telomeric, noncanonical roles for telomerase in regulating
stem cell function. In this study, human embryonic stem cells (hESCs) were cultured in 20 …

Telomerase (TERT) activation is a fundamental step in tumorigenesis. By maintaining
telomere length, telomerase relieves a main barrier on cellular lifespan, enabling limitless …

TERT gene is encoding for the telomerase enzyme catalytic subunit, which maintains
genomic integrity through de novo synthesis of telomere repeats at chromosome ends. It is …

Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase. Telomerase
complex plays a key role in cancer formation by telomere dependent or independent …

Activation of telomerase is a critical step in the development of about 85% of human
cancers. Levels of Tert, which encodes the reverse transcriptase subunit of telomerase, are …

Human telomerase, a ribonucleoprotein complex consisting of a catalytic subunit (hTERT)
and a RNA template component (TERC), prevents telomere attrition in human embryonic …