The functions of TRPA1 and TRPV1: moving away from sensory nerves
ES Fernandes, MA Fernandes… - British journal of …, 2012 - Wiley Online Library
The transient receptor potential vanilloid 1 and ankyrin 1 (TRPV1 and TRPA1, respectively)
channels are members of the TRP superfamily of structurally related, non‐selective cation …
channels are members of the TRP superfamily of structurally related, non‐selective cation …
Pleiotropic function of TRPV4 ion channels in the central nervous system
P Kanju, W Liedtke - Experimental physiology, 2016 - Wiley Online Library
New Findings What is the topic of this review? In this concise review, we highlight insights
into the role of transient receptor potential, vanilloid type 4 (TRPV4) ion channels in the …
into the role of transient receptor potential, vanilloid type 4 (TRPV4) ion channels in the …
The role of TRPA1 in visceral inflammation and pain
TK Lapointe, C Altier - Channels, 2011 - Taylor & Francis
Despite significant progress in our understanding of the cellular and molecular mechanisms
underlying sensory transduction and nociception, clinical pain management remains a …
underlying sensory transduction and nociception, clinical pain management remains a …
TRP channels in nociception and pathological pain
CY Hung, CH Tan - Advances in pain research: mechanisms and …, 2018 - Springer
Thermal and noxious stimuli are detected by specialized nerve endings, which transform the
stimuli into electrical signals and transmit the signals into central nervous system to facilitate …
stimuli into electrical signals and transmit the signals into central nervous system to facilitate …
TRPV1 in the central nervous system: synaptic plasticity, function, and pharmacological implications
JG Edwards - Capsaicin as a therapeutic molecule, 2014 - Springer
The function of TRPV1 in the peripheral nervous system is increasingly being investigated
for its anti-inflammatory and antinociceptive properties in an effort to find a novel target to …
for its anti-inflammatory and antinociceptive properties in an effort to find a novel target to …
TRP channels role in pain associated with neurodegenerative diseases
M Duitama, V Vargas-López, Z Casas… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) are cation channels expressed in both non-excitable and
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
A Szallasi, MJ Gunthorpe - Current pharmaceutical design, 2008 - ingentaconnect.com
Based on the painful effects of exposure to capsaicin, TRPV1 (transient receptor potential
vanilloid subfamily member 1) lo-calization is most readily associated with peripheral …
vanilloid subfamily member 1) lo-calization is most readily associated with peripheral …
Capsaicin receptor: TRPV1 a promiscuous TRP channel
TRPV1, the archetypal member of the vanilloid TRP family, was initially identified as the
receptor for capsaicin, the pungent ingredient in hot chili peppers. The receptor has a …
receptor for capsaicin, the pungent ingredient in hot chili peppers. The receptor has a …
Modulation of the TRPV1 channel: current clinical trials and recent patents with focus on neurological conditions
L De Petrocellis, AS Moriello - Recent Patents on CNS Drug …, 2013 - ingentaconnect.com
The transient receptor potential vanilloid-1 cat ion channel (TRPV1) is a nonspecific cation
channel that can be activated by multiple endogenous stimuli and is expressed …
channel that can be activated by multiple endogenous stimuli and is expressed …
TRPs in pain sensation
I Jardín, JJ López, R Diez, J Sánchez-Collado… - Frontiers in …, 2017 - frontiersin.org
According to the International Association for the Study of Pain (IASP) pain is characterized
as an “unpleasant sensory and emotional experience associated with actual or potential …
as an “unpleasant sensory and emotional experience associated with actual or potential …