Type IV pili of Streptococcus sanguinis contribute to pathogenesis in experimental infective endocarditis

AM Martini, BS Moricz, LJ Woods… - Microbiology …, 2021 - Am Soc Microbiol
Streptococcus sanguinis is a common cause of infective endocarditis (IE). Efforts by
research groups are aimed at identifying and characterizing virulence factors that contribute …

Association of Novel Streptococcus sanguinis Virulence Factors With Pathogenesis in a Native Valve Infective Endocarditis Model

AM Martini, BS Moricz, AK Ripperger, PM Tran… - Frontiers in …, 2020 - frontiersin.org
Streptococcus sanguinis (S. sanguinis) is an abundant oral commensal which can cause
disseminated human infection if it gains access to the bloodstream. The most important …

Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion

N Okahashi, M Nakata, A Sakurai, Y Terao… - Biochemical and …, 2010 - Elsevier
Streptococcus sanguinis is a predominant bacterium in the human oral cavity and
occasionally causes infective endocarditis. We identified a unique cell surface polymeric …

Streptococcus gallolyticus subsp. gallolyticus endocarditis isolate interferes with coagulation and activates the contact system

J Isenring, J Köhler, M Nakata, M Frank, C Jans… - Virulence, 2018 - Taylor & Francis
Streptococcus gallolyticus subsp. gallolyticus, formerly classified as S. bovis biotype I, is an
increasing cause of bacteremia and infective endocarditis in the elderly. The …

Identification of Streptococcus sanguinis Genes Required for Biofilm Formation and Examination of Their Role in Endocarditis Virulence

X Ge, T Kitten, Z Chen, SP Lee, CL Munro… - Infection and …, 2008 - Am Soc Microbiol
Streptococcus sanguinis is one of the pioneers in the bacterial colonization of teeth and is
one of the most abundant species in the oral biofilm called dental plaque. S. sanguinis is …

Comprehensive Evaluation of Streptococcus sanguinis Cell Wall-Anchored Proteins in Early Infective Endocarditis

LS Turner, T Kanamoto, T Unoki, CL Munro… - Infection and …, 2009 - Am Soc Microbiol
Streptococcus sanguinis is a member of the viridans group of streptococci and a leading
cause of the life-threatening endovascular disease infective endocarditis. Initial contact with …

Molecular Characterization of a Streptococcus gallolyticus Genomic Island Encoding a Pilus Involved in Endocarditis

C Danne, JM Entenza, A Mallet… - The Journal of …, 2011 - academic.oup.com
Background. Streptococcus gallolyticus is a causative agent of infective endocarditis
associated with colon cancer. Genome sequence of strain UCN34 revealed the existence of …

Contribution of the Interaction of Streptococcus mutans Serotype k Strains with Fibrinogen to the Pathogenicity of Infective Endocarditis

R Nomura, M Otsugu, S Naka, N Teramoto… - Infection and …, 2014 - Am Soc Microbiol
Streptococcus mutans, a pathogen responsible for dental caries, is occasionally isolated
from the blood of patients with bacteremia and infective endocarditis (IE). Our previous study …

Prevalence of type IV pili-mediated twitching motility in Streptococcus sanguinis strains and its impact on biofilm formation and host adherence

YYM Chen, HY Wang, CH Wu, YJ Lin… - Applied and …, 2022 - Am Soc Microbiol
Type IV pili (Tfp) are known to mediate several biological activities, including surface-
dependent twitching motility. Although a pil gene cluster for Tfp biosynthesis is found in all …

Genomic, Phenotypic, and Virulence Analysis of Streptococcus sanguinis Oral and Infective-Endocarditis Isolates

SP Baker, TJ Nulton, T Kitten - Infection and Immunity, 2019 - Am Soc Microbiol
Streptococcus sanguinis, an abundant and benign inhabitant of the oral cavity, is an
important etiologic agent of infective endocarditis (IE), particularly in people with …